Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 10 studies | 34% ± 14% | |
glutamatergic neuron | 8 studies | 43% ± 24% | |
astrocyte | 8 studies | 30% ± 12% | |
GABAergic neuron | 7 studies | 48% ± 24% | |
retinal ganglion cell | 6 studies | 57% ± 23% | |
retinal cone cell | 6 studies | 30% ± 11% | |
oligodendrocyte | 6 studies | 25% ± 6% | |
neuron | 5 studies | 25% ± 10% | |
interneuron | 5 studies | 48% ± 26% | |
retina horizontal cell | 5 studies | 37% ± 5% | |
amacrine cell | 4 studies | 22% ± 3% | |
retinal bipolar neuron | 4 studies | 26% ± 3% | |
endothelial cell | 3 studies | 30% ± 10% | |
GABAergic interneuron | 3 studies | 31% ± 4% | |
CD4-positive, alpha-beta T cell | 3 studies | 18% ± 1% | |
OFF-bipolar cell | 3 studies | 26% ± 13% | |
ON-bipolar cell | 3 studies | 38% ± 15% | |
rod bipolar cell | 3 studies | 40% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 8049.99 | 2641 / 2642 | 99% | 24.13 | 701 / 705 |
intestine | 72% | 1386.06 | 692 / 966 | 75% | 5.67 | 396 / 527 |
kidney | 53% | 710.88 | 47 / 89 | 59% | 4.26 | 531 / 901 |
muscle | 100% | 8195.25 | 799 / 803 | 0% | 0 | 0 / 0 |
skin | 1% | 19.58 | 14 / 1809 | 94% | 14.03 | 443 / 472 |
stomach | 26% | 429.53 | 95 / 359 | 64% | 5.04 | 183 / 286 |
adrenal gland | 7% | 70.33 | 18 / 258 | 82% | 7.43 | 188 / 230 |
prostate | 7% | 74.80 | 18 / 245 | 73% | 6.93 | 365 / 502 |
eye | 0% | 0 | 0 / 0 | 79% | 4.39 | 63 / 80 |
bladder | 33% | 448.10 | 7 / 21 | 37% | 2.73 | 185 / 504 |
breast | 39% | 740.70 | 177 / 459 | 25% | 1.18 | 283 / 1118 |
adipose | 61% | 1190.83 | 731 / 1204 | 0% | 0 | 0 / 0 |
liver | 8% | 101.81 | 17 / 226 | 49% | 3.24 | 198 / 406 |
pancreas | 2% | 19.41 | 7 / 328 | 53% | 2.38 | 94 / 178 |
peripheral blood | 51% | 1559.83 | 476 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 45% | 1.74 | 13 / 29 |
uterus | 1% | 10.99 | 2 / 170 | 41% | 2.96 | 190 / 459 |
esophagus | 7% | 66.97 | 95 / 1445 | 34% | 2.14 | 62 / 183 |
heart | 38% | 449.16 | 326 / 861 | 0% | 0 | 0 / 0 |
ovary | 4% | 44.85 | 8 / 180 | 27% | 1.44 | 118 / 430 |
spleen | 28% | 285.12 | 67 / 241 | 0% | 0 | 0 / 0 |
lung | 1% | 7.56 | 5 / 578 | 24% | 1.27 | 275 / 1155 |
thymus | 3% | 31.77 | 21 / 653 | 19% | 0.99 | 117 / 605 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.79 | 7 / 45 |
blood vessel | 3% | 51.30 | 45 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0016567 | Biological process | protein ubiquitination |
GO_1903861 | Biological process | positive regulation of dendrite extension |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0044297 | Cellular component | cell body |
GO_0005737 | Cellular component | cytoplasm |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | RNF157 |
Protein name | E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) Ring finger protein 157 E3 ubiquitin-protein ligase (EC 2.3.2.27) (RING-type E3 ubiquitin transferase) |
Synonyms | hCG_1817977 KIAA1917 |
Description | FUNCTION: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons . Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical . May act as a scaffold molecule to regulate this process . Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle . . FUNCTION: E3 ubiquitin ligase. . FUNCTION: E3 ubiquitin ligase. . FUNCTION: E3 ubiquitin ligase. . FUNCTION: E3 ubiquitin ligase. . |
Accessions | K7ENU4 A0A3B3ISM3 ENST00000591615.1 Q9BTC5 ENST00000591355.1 ENST00000319945.10 [Q96PX1-2] Q96PX1 K7EKB4 ENST00000592271.1 K7ER42 ENST00000269391.11 [Q96PX1-1] ENST00000647930.1 |