Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 7 studies | 20% ± 2% | |
oligodendrocyte | 7 studies | 25% ± 8% | |
epithelial cell | 6 studies | 30% ± 13% | |
squamous epithelial cell | 4 studies | 42% ± 19% | |
glutamatergic neuron | 4 studies | 42% ± 14% | |
neuron | 4 studies | 22% ± 5% | |
ciliated cell | 4 studies | 26% ± 8% | |
hepatocyte | 4 studies | 40% ± 17% | |
goblet cell | 4 studies | 26% ± 8% | |
B cell | 3 studies | 17% ± 2% | |
GABAergic neuron | 3 studies | 39% ± 3% | |
granule cell | 3 studies | 25% ± 7% | |
interneuron | 3 studies | 44% ± 25% | |
astrocyte | 3 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2479.93 | 180 / 180 | 100% | 36.12 | 430 / 430 |
prostate | 100% | 2661.27 | 245 / 245 | 100% | 40.11 | 502 / 502 |
stomach | 100% | 2340.52 | 359 / 359 | 100% | 39.95 | 286 / 286 |
esophagus | 100% | 5174.96 | 1444 / 1445 | 100% | 49.42 | 183 / 183 |
brain | 100% | 5908.28 | 2638 / 2642 | 100% | 35.19 | 705 / 705 |
intestine | 100% | 4136.18 | 966 / 966 | 100% | 40.02 | 526 / 527 |
breast | 100% | 3218.77 | 459 / 459 | 100% | 50.59 | 1115 / 1118 |
uterus | 100% | 3410.38 | 170 / 170 | 99% | 40.31 | 456 / 459 |
lung | 99% | 2542.80 | 574 / 578 | 100% | 36.72 | 1154 / 1155 |
bladder | 100% | 3143.00 | 21 / 21 | 99% | 33.43 | 499 / 504 |
liver | 100% | 3719.88 | 226 / 226 | 98% | 34.99 | 399 / 406 |
thymus | 100% | 2334.86 | 651 / 653 | 99% | 32.81 | 596 / 605 |
pancreas | 98% | 1788.68 | 321 / 328 | 99% | 32.54 | 177 / 178 |
skin | 100% | 4468.30 | 1808 / 1809 | 97% | 34.97 | 457 / 472 |
kidney | 100% | 2410.07 | 89 / 89 | 96% | 29.22 | 867 / 901 |
adrenal gland | 100% | 2881.40 | 258 / 258 | 95% | 25.71 | 218 / 230 |
adipose | 100% | 3374.17 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 27.88 | 29 / 29 |
muscle | 100% | 8640.62 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2932.72 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 39.04 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.98 | 1 / 1 |
blood vessel | 100% | 2561.00 | 1331 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 33.08 | 79 / 80 |
heart | 98% | 4338.31 | 841 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 2594.43 | 888 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0034657 | Cellular component | GID complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | RMND5A |
Protein name | E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A) |
Synonyms | |
Description | FUNCTION: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex . Catalytic activity of the complex is required for normal cell proliferation . The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 . . |
Accessions | ENST00000283632.5 [Q9H871-1] Q9H871 |