I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 5 studies | 35% ± 16% | |
| squamous epithelial cell | 3 studies | 29% ± 9% | |
| ciliated cell | 3 studies | 32% ± 19% | |
| epithelial cell | 3 studies | 47% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 5 studies | 35% ± 16% | |
| squamous epithelial cell | 3 studies | 29% ± 9% | |
| ciliated cell | 3 studies | 32% ± 19% | |
| epithelial cell | 3 studies | 47% ± 17% |
Insufficient scRNA-seq data for expression of RIPK4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 1171.63 | 328 / 328 | 98% | 27.66 | 174 / 178 |
| thymus | 99% | 1358.66 | 647 / 653 | 95% | 23.62 | 575 / 605 |
| kidney | 100% | 1588.54 | 89 / 89 | 94% | 29.93 | 847 / 901 |
| prostate | 89% | 1735.68 | 217 / 245 | 96% | 21.25 | 484 / 502 |
| lung | 89% | 693.68 | 512 / 578 | 95% | 26.93 | 1094 / 1155 |
| liver | 99% | 1516.32 | 224 / 226 | 83% | 13.76 | 339 / 406 |
| stomach | 76% | 1225.46 | 273 / 359 | 95% | 17.64 | 271 / 286 |
| skin | 72% | 2317.59 | 1305 / 1809 | 76% | 35.43 | 357 / 472 |
| esophagus | 45% | 3723.01 | 653 / 1445 | 99% | 40.95 | 181 / 183 |
| bladder | 48% | 695.38 | 10 / 21 | 95% | 31.60 | 481 / 504 |
| intestine | 47% | 383.15 | 456 / 966 | 95% | 18.03 | 500 / 527 |
| breast | 57% | 811.93 | 262 / 459 | 70% | 10.00 | 783 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 67.72 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.19 | 1 / 1 |
| ovary | 0% | 0 | 0 / 180 | 94% | 20.49 | 403 / 430 |
| uterus | 6% | 102.26 | 10 / 170 | 88% | 40.96 | 403 / 459 |
| eye | 0% | 0 | 0 / 0 | 93% | 17.14 | 74 / 80 |
| blood vessel | 86% | 1006.58 | 1152 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 17% | 99.81 | 210 / 1204 | 0% | 0 | 0 / 0 |
| heart | 10% | 48.42 | 85 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 2.94 | 1 / 258 | 2% | 0.33 | 5 / 230 |
| peripheral blood | 2% | 12.15 | 21 / 929 | 0% | 0 | 0 / 0 |
| spleen | 0% | 2.04 | 1 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.88 | 2 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 1.55 | 6 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051092 | Biological process | positive regulation of NF-kappaB transcription factor activity |
| GO_0002009 | Biological process | morphogenesis of an epithelium |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | RIPK4 |
| Protein name | Receptor-interacting serine-threonine kinase 4 Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase) |
| Synonyms | ANKRD3 DIK hCG_401241 |
| Description | FUNCTION: Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation. . |
| Accessions | ENST00000352483.3 [P57078-1] P57078 Q2TB16 ENST00000332512.8 [P57078-2] |
