RHEBL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RHEBL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RHEBL1 at tissue level.

III. Associated gene sets

GO_0031929Biological processTOR signaling
GO_0051092Biological processpositive regulation of NF-kappaB transcription factor activity
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0005886Cellular componentplasma membrane
GO_0012505Cellular componentendomembrane system
GO_0005737Cellular componentcytoplasm
GO_0019003Molecular functionGDP binding
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRHEBL1
Protein nameRHEB like 1
GTPase RhebL1 (Ras homolog enriched in brain like-1 c) (RhebL1c) (Ras homolog enriched in brain-like protein 1) (Rheb-like protein 1) (Rheb2)
Alternative protein RHEBL1
Synonyms
DescriptionFUNCTION: Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. .

AccessionsF8W1T5
ENST00000550675.1
ENST00000301068.11 [Q8TAI7-1]
Q8TAI7
ENST00000420065.5
C9JQQ1
L8EBD9
ENST00000550797.1 [Q8TAI7-2]