I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythrocyte | 8 studies | 54% ± 18% | |
| erythroblast | 4 studies | 58% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| erythrocyte | 8 studies | 54% ± 18% | |
| erythroblast | 4 studies | 58% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 42% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| heart | 89% | 86.03 | 769 / 861 | 0% | 0 | 0 / 0 |
| spleen | 80% | 143.17 | 194 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 80% | 356.72 | 744 / 929 | 0% | 0 | 0 / 0 |
| intestine | 75% | 35.84 | 723 / 966 | 2% | 0.07 | 10 / 527 |
| bladder | 76% | 17.24 | 16 / 21 | 0% | 0.01 | 2 / 504 |
| prostate | 67% | 23.69 | 163 / 245 | 7% | 0.32 | 37 / 502 |
| esophagus | 66% | 37.92 | 950 / 1445 | 3% | 0.13 | 5 / 183 |
| lung | 52% | 23.56 | 302 / 578 | 1% | 0.04 | 6 / 1155 |
| stomach | 47% | 19.36 | 167 / 359 | 3% | 0.08 | 10 / 286 |
| uterus | 44% | 15.51 | 74 / 170 | 0% | 0 | 0 / 459 |
| thymus | 43% | 9.26 | 280 / 653 | 0% | 0 | 0 / 605 |
| blood vessel | 32% | 14.22 | 425 / 1335 | 0% | 0 | 0 / 0 |
| liver | 29% | 12.39 | 66 / 226 | 1% | 0.06 | 5 / 406 |
| adipose | 30% | 10.31 | 362 / 1204 | 0% | 0 | 0 / 0 |
| breast | 26% | 5.20 | 120 / 459 | 1% | 0.03 | 13 / 1118 |
| skin | 20% | 3.49 | 363 / 1809 | 2% | 0.05 | 8 / 472 |
| kidney | 18% | 4.04 | 16 / 89 | 3% | 0.13 | 23 / 901 |
| ovary | 16% | 5.07 | 29 / 180 | 0% | 0.01 | 2 / 430 |
| adrenal gland | 6% | 1.19 | 15 / 258 | 2% | 0.10 | 4 / 230 |
| pancreas | 6% | 0.92 | 20 / 328 | 1% | 0.02 | 2 / 178 |
| brain | 5% | 1.37 | 129 / 2642 | 0% | 0.01 | 3 / 705 |
| muscle | 4% | 1.79 | 30 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0048821 | Biological process | erythrocyte development |
| GO_0035378 | Biological process | carbon dioxide transmembrane transport |
| GO_0006873 | Biological process | intracellular monoatomic ion homeostasis |
| GO_0015670 | Biological process | carbon dioxide transport |
| GO_0072489 | Biological process | methylammonium transmembrane transport |
| GO_0072488 | Biological process | ammonium transmembrane transport |
| GO_0060586 | Biological process | multicellular organismal-level iron ion homeostasis |
| GO_0098662 | Biological process | inorganic cation transmembrane transport |
| GO_0097272 | Biological process | ammonium homeostasis |
| GO_0015701 | Biological process | bicarbonate transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0170014 | Cellular component | ankyrin-1 complex |
| GO_0022840 | Molecular function | leak channel activity |
| GO_0015200 | Molecular function | methylammonium transmembrane transporter activity |
| GO_0008519 | Molecular function | ammonium channel activity |
| GO_0030506 | Molecular function | ankyrin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0035379 | Molecular function | carbon dioxide transmembrane transporter activity |
| Gene name | RHAG |
| Protein name | Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) Rh-associated glycoprotein Truncated RhAG glycoprotein RHAG Abnormal Rhesus blood group-associated glycoprotein (Erythrocyte membrane glycoprotein Rh50) (Rh50 glycoprotein) Truncated Rh-associated glycoprotein Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Erythrocyte plasma membrane 50 kDa glycoprotein) (Rh50A) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (Rhesus blood group-associated ammonia channel) (Rhesus blood group-associated glycoprotein) (CD antigen CD241) |
| Synonyms | hCG_20861 RH50 |
| Description | FUNCTION: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane . Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane . The transport of NH4(+) is electrogenic and masks the NH3 transport . Also, may act as a CO2 channel . In vitro, leaks monovalent cations . Moreover in erythrocyte, regulates RHD membrane expression and is associated with rhesus blood group antigen expression . . |
| Accessions | ENST00000371175.10 [Q02094-1] M1SZX7 A0A023UN48 ENST00000646963.1 Q02094 A0A7S8MU46 A0A7S8RGC4 A0A248X8V9 M5FJR4 A0A8D5ZBQ7 A0A411HBG8 Q9UK69 A0A3G2FPG1 ENST00000646939.1 [Q02094-2] A0A7D4WXE7 A0A1A9C9I6 A0A2R8YEH1 A0A0A8IKZ2 A0A0A1TSG9 Q9UHG9 A0A6S6PEI8 A0A6S4QW46 A0A1Q1NHH4 ENST00000646272.1 Q9UBB8 A0A1D8RAA9 X5MNR9 Q96E98 A0A7S8RFX7 |
