RGS9BP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RGS9BP at tissue level.

III. Associated gene sets

GO_0050908Biological processdetection of light stimulus involved in visual perception
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0009968Biological processnegative regulation of signal transduction
GO_0043005Cellular componentneuron projection
GO_0016020Cellular componentmembrane

IV. Literature review

[source]
Gene nameRGS9BP
Protein nameRegulator of G-protein signaling 9-binding protein (RGS9-anchoring protein)
SynonymsR9AP
DescriptionFUNCTION: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity). .

AccessionsQ6ZS82
ENST00000334176.4