Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 25% ± 12% | |
pericyte | 5 studies | 22% ± 8% | |
epithelial cell | 5 studies | 35% ± 19% | |
classical monocyte | 4 studies | 27% ± 7% | |
natural killer cell | 4 studies | 19% ± 2% | |
B cell | 3 studies | 20% ± 6% | |
conventional dendritic cell | 3 studies | 32% ± 11% | |
hematopoietic precursor cell | 3 studies | 31% ± 7% | |
non-classical monocyte | 3 studies | 28% ± 5% | |
fibroblast | 3 studies | 21% ± 6% | |
ciliated cell | 3 studies | 33% ± 8% | |
CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
dendritic cell | 3 studies | 33% ± 11% | |
plasmacytoid dendritic cell | 3 studies | 24% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 4 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1235.18 | 1445 / 1445 | 100% | 24.65 | 183 / 183 |
ovary | 100% | 1186.01 | 180 / 180 | 100% | 99.10 | 430 / 430 |
skin | 100% | 1357.44 | 1809 / 1809 | 100% | 50.18 | 472 / 472 |
thymus | 100% | 1882.32 | 653 / 653 | 100% | 68.33 | 605 / 605 |
brain | 100% | 814.56 | 2637 / 2642 | 100% | 46.76 | 705 / 705 |
uterus | 100% | 1350.99 | 170 / 170 | 100% | 65.57 | 458 / 459 |
kidney | 100% | 1363.99 | 89 / 89 | 99% | 37.57 | 896 / 901 |
pancreas | 100% | 751.65 | 328 / 328 | 99% | 36.39 | 177 / 178 |
breast | 100% | 1351.26 | 459 / 459 | 99% | 47.51 | 1111 / 1118 |
prostate | 100% | 1466.75 | 245 / 245 | 99% | 48.48 | 498 / 502 |
intestine | 100% | 1290.35 | 966 / 966 | 99% | 41.08 | 521 / 527 |
lung | 100% | 1239.99 | 578 / 578 | 99% | 40.61 | 1141 / 1155 |
stomach | 100% | 1092.23 | 359 / 359 | 99% | 34.13 | 282 / 286 |
bladder | 100% | 1120.62 | 21 / 21 | 98% | 48.91 | 495 / 504 |
adrenal gland | 100% | 875.72 | 258 / 258 | 97% | 26.76 | 223 / 230 |
liver | 99% | 464.22 | 224 / 226 | 97% | 26.42 | 392 / 406 |
adipose | 100% | 1214.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 54.96 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 103.47 | 29 / 29 |
peripheral blood | 100% | 1725.98 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 1686.59 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 52.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 37.64 | 1 / 1 |
blood vessel | 100% | 905.25 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 742.90 | 858 / 861 | 0% | 0 | 0 / 0 |
muscle | 100% | 790.01 | 800 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0045348 | Biological process | positive regulation of MHC class II biosynthetic process |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0045171 | Cellular component | intercellular bridge |
GO_0005634 | Cellular component | nucleus |
GO_0042826 | Molecular function | histone deacetylase binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | RFXANK |
Protein name | RFXANK protein Regulatory factor X associated ankyrin containing protein Regulatory factor X associated ankyrin containing protein (Regulatory factor X-associated ankyrin-containing protein, isoform CRA_c) DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) |
Synonyms | RFXB hCG_38560 ANKRA1 |
Description | FUNCTION: Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters . May also potentiate the activation of RAF1 (By similarity). .; FUNCTION: Isoform 2 is not involved in the positive regulation of MHC class II genes. . |
Accessions | ENST00000456252.7 [O14593-3] ENST00000421262.7 ENST00000536253.1 ENST00000544923.5 H0YFU5 H0YGQ6 ENST00000392324.8 ENST00000540981.5 ENST00000535017.1 Q6IB23 ENST00000593273.5 O14593 H0YFZ0 ENST00000407360.7 [O14593-1] A0A024R7P0 F5H7D2 F5GY33 K7ENE6 ENST00000303088.9 [O14593-1] |