RFTN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0033227Biological processdsRNA transport
GO_0043330Biological processresponse to exogenous dsRNA
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRFTN2
Protein nameRaftlin family member 2
Raftlin-2 (Raft-linking protein 2)
SynonymsC2orf11
DescriptionFUNCTION: Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. .

AccessionsQ52LD8
C9J6C2
ENST00000429081.1
ENST00000295049.9
H7BZ31
ENST00000454447.1