Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 20% ± 4% | |
epithelial cell | 5 studies | 26% ± 5% | |
astrocyte | 4 studies | 21% ± 3% | |
glutamatergic neuron | 4 studies | 39% ± 16% | |
macrophage | 4 studies | 17% ± 1% | |
type I pneumocyte | 3 studies | 18% ± 1% | |
GABAergic neuron | 3 studies | 38% ± 8% | |
oligodendrocyte precursor cell | 3 studies | 25% ± 4% | |
natural killer cell | 3 studies | 16% ± 0% | |
goblet cell | 3 studies | 21% ± 4% | |
interneuron | 3 studies | 33% ± 17% | |
neuron | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3648.57 | 21 / 21 | 100% | 61.84 | 504 / 504 |
breast | 100% | 3273.47 | 459 / 459 | 100% | 78.05 | 1118 / 1118 |
liver | 100% | 3127.00 | 226 / 226 | 100% | 51.53 | 406 / 406 |
lung | 100% | 3341.64 | 578 / 578 | 100% | 60.45 | 1155 / 1155 |
pancreas | 100% | 4145.72 | 328 / 328 | 100% | 55.65 | 178 / 178 |
prostate | 100% | 4981.68 | 245 / 245 | 100% | 77.02 | 502 / 502 |
skin | 100% | 4646.64 | 1809 / 1809 | 100% | 62.74 | 472 / 472 |
stomach | 100% | 3229.63 | 359 / 359 | 100% | 39.08 | 286 / 286 |
uterus | 100% | 4017.52 | 170 / 170 | 100% | 55.30 | 459 / 459 |
esophagus | 100% | 3741.49 | 1444 / 1445 | 100% | 45.76 | 183 / 183 |
thymus | 100% | 3299.26 | 653 / 653 | 100% | 63.72 | 604 / 605 |
intestine | 100% | 3557.15 | 966 / 966 | 100% | 41.30 | 526 / 527 |
kidney | 100% | 2853.93 | 89 / 89 | 100% | 57.56 | 899 / 901 |
brain | 99% | 2687.24 | 2626 / 2642 | 100% | 45.57 | 705 / 705 |
adrenal gland | 100% | 3854.19 | 258 / 258 | 99% | 41.06 | 228 / 230 |
ovary | 100% | 3521.60 | 180 / 180 | 99% | 27.13 | 426 / 430 |
adipose | 100% | 2936.86 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 57.12 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 62.29 | 29 / 29 |
spleen | 100% | 5533.15 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 62.11 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 59.21 | 1 / 1 |
muscle | 100% | 2353.14 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2295.34 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1628.07 | 850 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 3401.30 | 915 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071786 | Biological process | endoplasmic reticulum tubular network organization |
GO_0061709 | Biological process | reticulophagy |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0030574 | Biological process | collagen catabolic process |
GO_0071782 | Cellular component | endoplasmic reticulum tubular network |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0140506 | Molecular function | endoplasmic reticulum-autophagosome adaptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | RETREG3 |
Protein name | Reticulophagy regulator 3 Reticulophagy regulator family member 3 |
Synonyms | FAM134C |
Description | FUNCTION: Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress . When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins . Promotes ER membrane curvature and ER tubulation required for subsequent ER fragmentation and engulfment into autophagosomes . Required for collagen quality control in a LIR motif-dependent manner (By similarity). Mediates NRF1-enhanced neurite outgrowth . . |
Accessions | ENST00000585726.5 ENST00000585894.5 ENST00000586870.5 K7ENF4 ENST00000591547.5 K7EQI9 ENST00000593251.5 K7EMF4 K7ENZ6 K7EJ42 K7ELM8 ENST00000589797.5 ENST00000590541.1 ENST00000588423.1 K7EPD0 ENST00000309428.10 [Q86VR2-1] K7EJ34 Q86VR2 |