RERG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009725Biological processresponse to hormone
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0030308Biological processnegative regulation of cell growth
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0001650Cellular componentfibrillar center
GO_0005634Cellular componentnucleus
GO_0019003Molecular functionGDP binding
GO_0005525Molecular functionGTP binding
GO_0003924Molecular functionGTPase activity
GO_0003925Molecular functionG protein activity
GO_0030331Molecular functionnuclear estrogen receptor binding

IV. Literature review

[source]
Gene nameRERG
Protein namesmall monomeric GTPase (EC 3.6.5.2)
Ras-related and estrogen-regulated growth inhibitor (EC 3.6.5.2)
Synonyms
DescriptionFUNCTION: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. .

AccessionsENST00000256953.6 [Q96A58-1]
ENST00000393736.3
ENST00000537647.5
ENST00000545567.5
ENST00000546331.5 [Q96A58-2]
F5GYR1
ENST00000538313.5 [Q96A58-1]
Q96A58
F5GWE9
F5H252
ENST00000536465.5 [Q96A58-1]