I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 32% ± 11% | |
| retinal cone cell | 4 studies | 26% ± 10% | |
| rod bipolar cell | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 32% ± 11% | |
| retinal cone cell | 4 studies | 26% ± 10% | |
| rod bipolar cell | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 5 studies | 25% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 72% | 86.74 | 64 / 89 | 2% | 0.45 | 17 / 901 |
| skin | 33% | 1.29 | 606 / 1809 | 35% | 8.64 | 166 / 472 |
| adipose | 58% | 3.18 | 693 / 1204 | 0% | 0 | 0 / 0 |
| breast | 44% | 2.21 | 204 / 459 | 0% | 0.00 | 3 / 1118 |
| esophagus | 19% | 0.54 | 273 / 1445 | 13% | 0.61 | 23 / 183 |
| bladder | 29% | 0.67 | 6 / 21 | 2% | 0.17 | 12 / 504 |
| liver | 22% | 1.12 | 50 / 226 | 7% | 0.48 | 30 / 406 |
| brain | 28% | 0.97 | 749 / 2642 | 1% | 0.03 | 5 / 705 |
| intestine | 23% | 0.75 | 223 / 966 | 5% | 0.17 | 27 / 527 |
| stomach | 17% | 0.58 | 62 / 359 | 10% | 0.87 | 29 / 286 |
| prostate | 26% | 0.80 | 63 / 245 | 0% | 0 | 0 / 502 |
| lung | 18% | 0.50 | 106 / 578 | 3% | 0.11 | 38 / 1155 |
| adrenal gland | 19% | 0.56 | 50 / 258 | 2% | 0.04 | 4 / 230 |
| blood vessel | 18% | 0.59 | 242 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 16% | 0.53 | 52 / 328 | 2% | 0.03 | 3 / 178 |
| heart | 17% | 0.77 | 150 / 861 | 0% | 0 | 0 / 0 |
| muscle | 17% | 0.46 | 139 / 803 | 0% | 0 | 0 / 0 |
| uterus | 16% | 0.45 | 28 / 170 | 1% | 0.01 | 3 / 459 |
| ovary | 13% | 0.34 | 24 / 180 | 2% | 0.05 | 10 / 430 |
| thymus | 15% | 0.45 | 101 / 653 | 0% | 0 | 0 / 605 |
| eye | 0% | 0 | 0 / 0 | 15% | 1.71 | 12 / 80 |
| peripheral blood | 15% | 0.50 | 139 / 929 | 0% | 0 | 0 / 0 |
| spleen | 7% | 0.20 | 16 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006703 | Biological process | estrogen biosynthetic process |
| GO_0007601 | Biological process | visual perception |
| GO_0042572 | Biological process | retinol metabolic process |
| GO_0006694 | Biological process | steroid biosynthetic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004303 | Molecular function | estradiol 17-beta-dehydrogenase [NAD(P)+] activity |
| GO_0004745 | Molecular function | all-trans-retinol dehydrogenase (NAD+) activity |
| GO_0052650 | Molecular function | all-trans-retinol dehydrogenase (NADP+) activity |
| Gene name | RDH8 |
| Protein name | Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 2) Retinol dehydrogenase 8 Retinol dehydrogenase (EC 1.1.1.300) |
| Synonyms | PRRDH SDR28C2 |
| Description | FUNCTION: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity (By similarity). . FUNCTION: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity. . |
| Accessions | ENST00000587782.1 Q9NYR8 ENST00000651512.1 ENST00000591589.3 K7ELF7 K7EKT5 |
