I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 28% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 28% ± 7% |
Insufficient scRNA-seq data for expression of RCE1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1070.39 | 1445 / 1445 | 100% | 25.68 | 183 / 183 |
| ovary | 100% | 1116.99 | 180 / 180 | 100% | 33.32 | 430 / 430 |
| pancreas | 100% | 744.94 | 328 / 328 | 100% | 25.88 | 178 / 178 |
| uterus | 100% | 1166.04 | 170 / 170 | 100% | 30.32 | 459 / 459 |
| lung | 100% | 946.07 | 578 / 578 | 100% | 26.44 | 1154 / 1155 |
| stomach | 100% | 832.01 | 359 / 359 | 100% | 25.78 | 285 / 286 |
| breast | 100% | 1022.77 | 459 / 459 | 100% | 27.10 | 1114 / 1118 |
| prostate | 100% | 1330.09 | 245 / 245 | 100% | 20.80 | 500 / 502 |
| skin | 100% | 1328.68 | 1809 / 1809 | 100% | 20.94 | 470 / 472 |
| intestine | 100% | 1057.59 | 966 / 966 | 99% | 27.86 | 524 / 527 |
| bladder | 100% | 893.19 | 21 / 21 | 99% | 30.24 | 501 / 504 |
| thymus | 100% | 885.67 | 653 / 653 | 99% | 15.14 | 601 / 605 |
| brain | 99% | 914.35 | 2605 / 2642 | 100% | 14.46 | 705 / 705 |
| kidney | 100% | 1363.04 | 89 / 89 | 98% | 14.64 | 886 / 901 |
| adrenal gland | 100% | 948.67 | 258 / 258 | 94% | 11.56 | 217 / 230 |
| liver | 99% | 445.63 | 223 / 226 | 95% | 12.62 | 386 / 406 |
| adipose | 100% | 944.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 18.16 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 21.82 | 29 / 29 |
| spleen | 100% | 1249.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.22 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 29.34 | 1 / 1 |
| blood vessel | 100% | 678.51 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 697.79 | 899 / 929 | 0% | 0 | 0 / 0 |
| heart | 96% | 401.54 | 826 / 861 | 0% | 0 | 0 / 0 |
| muscle | 70% | 189.55 | 560 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0071586 | Biological process | CAAX-box protein processing |
| GO_0018342 | Biological process | protein prenylation |
| GO_0000165 | Biological process | MAPK cascade |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0004175 | Molecular function | endopeptidase activity |
| GO_0004197 | Molecular function | cysteine-type endopeptidase activity |
| GO_0008238 | Molecular function | exopeptidase activity |
| Gene name | RCE1 |
| Protein name | Farnesylated proteins-converting enzyme 2 Ras converting CAAX endopeptidase 1 CAAX prenyl protease 2 (EC 3.4.-.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1) |
| Synonyms | FACE2 RCE1B RCE1A |
| Description | FUNCTION: Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 . . |
| Accessions | ENST00000309657.8 ENST00000524849.5 ENST00000524506.5 ENST00000525356.1 Q0P5W4 Q9Y256 E9PI08 E9PPV9 E9PKA7 |
