RBSN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034498Biological processearly endosome to Golgi transport
GO_0015031Biological processprotein transport
GO_0016197Biological processendosomal transport
GO_0090160Biological processGolgi to lysosome transport
GO_1903358Biological processregulation of Golgi organization
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0010008Cellular componentendosome membrane
GO_0031901Cellular componentearly endosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0005768Cellular componentendosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0031267Molecular functionsmall GTPase binding

IV. Literature review

[source]
Gene nameRBSN
Protein nameRabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20)
Rabenosyn, RAB effector
SynonymsZFYVE20
DescriptionFUNCTION: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) . Plays a role in the recycling of transferrin receptor to the plasma membrane . .

AccessionsC9JZZ1
ENST00000449050.5
H7C204
ENST00000253699.7 [Q9H1K0-1]
ENST00000426541.1
Q9H1K0
ENST00000441057.5
D6RD50
F8WE50
ENST00000507357.1
ENST00000476527.6 [Q9H1K0-1]