RBBP9 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RBBP9 at tissue level.

III. Associated gene sets

GO_0009624Biological processresponse to nematode
GO_0010628Biological processpositive regulation of gene expression
GO_0060510Biological processtype II pneumocyte differentiation
GO_0005654Cellular componentnucleoplasm
GO_0016787Molecular functionhydrolase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRBBP9
Protein nameSerine hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9)
SynonymsBOG
RBBP10
DescriptionFUNCTION: Serine hydrolase whose substrates have not been identified yet . May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation . May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 . .

AccessionsENST00000337227.9 [O75884-1]
O75884