RANBP3L report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RANBP3L at tissue level.

III. Associated gene sets

GO_1901706Biological processmesenchymal cell differentiation involved in bone development
GO_0045663Biological processpositive regulation of myoblast differentiation
GO_0006611Biological processprotein export from nucleus
GO_0045668Biological processnegative regulation of osteoblast differentiation
GO_0005737Cellular componentcytoplasm
GO_0005643Cellular componentnuclear pore
GO_0046332Molecular functionSMAD binding
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameRANBP3L
Protein nameRAN binding protein 3 like
Ran-binding protein 3-like
Synonyms
DescriptionFUNCTION: Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner. .

AccessionsENST00000515759.5 [Q86VV4-2]
ENST00000505865.1
Q86VV4
D6RCM9
ENST00000296604.8 [Q86VV4-1]
ENST00000502994.5 [Q86VV4-3]