RABGGTA report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RABGGTA at tissue level.

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0018344Biological processprotein geranylgeranylation
GO_0036211Biological processprotein modification process
GO_0005968Cellular componentRab-protein geranylgeranyltransferase complex
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0031267Molecular functionsmall GTPase binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0004663Molecular functionRab geranylgeranyltransferase activity

IV. Literature review

[source]
Gene nameRABGGTA
Protein nameGeranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha)
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
Rab geranylgeranyltransferase subunit alpha
Synonyms
DescriptionFUNCTION: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. .

FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences. .

FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences. .

FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences. .; FUNCTION: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. .

AccessionsENST00000644383.1
H0YKP6
ENST00000560521.5
ENST00000560127.1
H0YLG7
Q92696
ENST00000399409.7
Q6FHF7
ENST00000560777.5
ENST00000646658.1
ENST00000216840.11
ENST00000560243.5
H0YMG5
H0YLH3
H0YKZ8
ENST00000558376.5
ENST00000559974.5