RAB26 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045055Biological processregulated exocytosis
GO_0017157Biological processregulation of exocytosis
GO_0043001Biological processGolgi to plasma membrane protein transport
GO_0035272Biological processexocrine system development
GO_0140251Biological processregulation protein catabolic process at presynapse
GO_0000139Cellular componentGolgi membrane
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0030667Cellular componentsecretory granule membrane
GO_0005768Cellular componentendosome
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0005525Molecular functionGTP binding
GO_0019002Molecular functionGMP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB26
Protein nameRas-related protein Rab-26
RAB26, member RAS oncogene family
Synonyms
DescriptionFUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. .

AccessionsH3BMG6
ENST00000210187.11 [Q9ULW5-1]
Q9ULW5
ENST00000541451.5 [Q9ULW5-2]
ENST00000565592.5
ENST00000566724.1
H3BQ97