RAB11FIP4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032456Biological processendocytic recycling
GO_0032465Biological processregulation of cytokinesis
GO_0005813Cellular componentcentrosome
GO_0005615Cellular componentextracellular space
GO_0032154Cellular componentcleavage furrow
GO_0030496Cellular componentmidbody
GO_0005768Cellular componentendosome
GO_0055038Cellular componentrecycling endosome membrane
GO_0005819Cellular componentspindle
GO_0030139Cellular componentendocytic vesicle
GO_0042803Molecular functionprotein homodimerization activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding

IV. Literature review

[source]
Gene nameRAB11FIP4
Protein nameAlternative protein RAB11FIP4
Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2)
RAB11 family interacting protein 4
SynonymsKIAA1821
ARFO2
DescriptionFUNCTION: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6. .

AccessionsENST00000621161.5 [Q86YS3-1]
J3QLM3
K7EMK3
ENST00000582009.5
Q86YS3
J3QKR9
ENST00000578694.1
ENST00000583755.1
ENST00000579589.1
K7EL58
ENST00000394744.6 [Q86YS3-2]
L8ECL7