RAB11FIP2 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	9 studies	38% ± 15%	Explore
oligodendrocyte	9 studies	27% ± 7%	Explore
glutamatergic neuron	6 studies	43% ± 24%	Explore
endothelial cell	5 studies	36% ± 19%	Explore
microglial cell	5 studies	21% ± 5%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 8%	Explore
macrophage	5 studies	20% ± 5%	Explore
GABAergic neuron	4 studies	45% ± 15%	Explore
interneuron	4 studies	39% ± 21%	Explore
neuron	3 studies	29% ± 8%	Explore
epithelial cell	3 studies	24% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	39% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1718.84	1443 / 1445	100%	11.98	183 / 183
brain	100%	1952.85	2632 / 2642	100%	14.03	704 / 705
ovary	100%	2178.48	180 / 180	99%	15.07	425 / 430
prostate	100%	2178.40	245 / 245	99%	12.03	496 / 502
thymus	100%	2184.10	653 / 653	98%	14.92	594 / 605
breast	100%	1736.19	459 / 459	97%	10.30	1083 / 1118
lung	100%	1869.31	577 / 578	97%	9.12	1118 / 1155
kidney	100%	1858.17	89 / 89	96%	15.81	866 / 901
pancreas	99%	908.19	326 / 328	96%	8.86	171 / 178
adrenal gland	100%	1307.27	257 / 258	94%	11.33	217 / 230
stomach	100%	2718.12	359 / 359	93%	10.42	267 / 286
bladder	100%	2240.38	21 / 21	89%	7.95	448 / 504
skin	100%	1806.31	1808 / 1809	89%	10.18	419 / 472
uterus	100%	4461.51	170 / 170	88%	7.52	403 / 459
intestine	100%	1933.50	966 / 966	86%	7.46	455 / 527
liver	94%	531.92	212 / 226	65%	4.16	264 / 406
adipose	100%	1946.46	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2517.98	1335 / 1335	0%	0	0 / 0
spleen	100%	1374.17	241 / 241	0%	0	0 / 0
muscle	99%	845.17	791 / 803	0%	0	0 / 0
heart	95%	979.88	818 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	87%	4.64	39 / 45
lymph node	0%	0	0 / 0	79%	5.38	23 / 29
eye	0%	0	0 / 0	57%	4.14	46 / 80
peripheral blood	50%	433.85	463 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030010	Biological process	establishment of cell polarity
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0035773	Biological process	insulin secretion involved in cellular response to glucose stimulus
GO_0045055	Biological process	regulated exocytosis
GO_1903078	Biological process	positive regulation of protein localization to plasma membrane
GO_0006909	Biological process	phagocytosis
GO_0035669	Biological process	TRAM-dependent toll-like receptor 4 signaling pathway
GO_0055038	Cellular component	recycling endosome membrane
GO_0005654	Cellular component	nucleoplasm
GO_0001891	Cellular component	phagocytic cup
GO_0042995	Cellular component	cell projection
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005768	Cellular component	endosome
GO_0030659	Cellular component	cytoplasmic vesicle membrane
GO_0042803	Molecular function	protein homodimerization activity
GO_0019901	Molecular function	protein kinase binding
GO_0042802	Molecular function	identical protein binding
GO_0031267	Molecular function	small GTPase binding
GO_0005515	Molecular function	protein binding

Gene name	RAB11FIP2
Protein name	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11)
Synonyms	KIAA0941
Description	FUNCTION: A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics. .
Accessions	Q7L804 ENST00000355624.8 [Q7L804-1] ENST00000369199.5 [Q7L804-2]

RAB11FIP2 report