Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 16 studies | 57% ± 21% | |
| enteroendocrine cell | 6 studies | 44% ± 22% | |
| neuron | 6 studies | 44% ± 16% | |
| plasmacytoid dendritic cell | 6 studies | 25% ± 8% | |
| epithelial cell of proximal tubule | 5 studies | 38% ± 10% | |
| endothelial cell | 5 studies | 24% ± 6% | |
| glutamatergic neuron | 5 studies | 40% ± 19% | |
| astrocyte | 5 studies | 27% ± 10% | |
| hepatocyte | 5 studies | 38% ± 23% | |
| pancreatic A cell | 4 studies | 69% ± 17% | |
| microglial cell | 4 studies | 30% ± 10% | |
| retinal ganglion cell | 4 studies | 60% ± 28% | |
| epithelial cell | 4 studies | 36% ± 14% | |
| Mueller cell | 4 studies | 47% ± 17% | |
| macrophage | 4 studies | 25% ± 6% | |
| GABAergic neuron | 4 studies | 37% ± 14% | |
| oligodendrocyte precursor cell | 4 studies | 31% ± 12% | |
| pancreatic D cell | 3 studies | 60% ± 26% | |
| type B pancreatic cell | 3 studies | 45% ± 13% | |
| hematopoietic precursor cell | 3 studies | 18% ± 2% | |
| retina horizontal cell | 3 studies | 27% ± 9% | |
| fibroblast | 3 studies | 21% ± 6% | |
| dendritic cell | 3 studies | 32% ± 4% | |
| intestinal crypt stem cell | 3 studies | 18% ± 2% | |
| interneuron | 3 studies | 31% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 20899.30 | 2642 / 2642 | 100% | 165.64 | 705 / 705 |
| liver | 100% | 7846.61 | 226 / 226 | 99% | 92.56 | 403 / 406 |
| adrenal gland | 100% | 4307.13 | 258 / 258 | 99% | 341.42 | 227 / 230 |
| kidney | 94% | 4421.44 | 84 / 89 | 98% | 48.28 | 884 / 901 |
| breast | 88% | 2127.23 | 404 / 459 | 97% | 95.03 | 1079 / 1118 |
| prostate | 76% | 1522.67 | 185 / 245 | 99% | 77.10 | 496 / 502 |
| thymus | 73% | 1308.07 | 474 / 653 | 95% | 31.59 | 577 / 605 |
| skin | 64% | 1270.19 | 1153 / 1809 | 97% | 134.75 | 458 / 472 |
| intestine | 66% | 1153.88 | 634 / 966 | 93% | 37.24 | 490 / 527 |
| uterus | 65% | 1045.30 | 110 / 170 | 88% | 28.90 | 406 / 459 |
| lung | 62% | 1240.84 | 361 / 578 | 90% | 26.26 | 1034 / 1155 |
| ovary | 51% | 817.83 | 92 / 180 | 93% | 27.36 | 398 / 430 |
| stomach | 50% | 809.56 | 179 / 359 | 91% | 29.08 | 260 / 286 |
| bladder | 48% | 747.90 | 10 / 21 | 88% | 28.32 | 442 / 504 |
| pancreas | 34% | 512.77 | 111 / 328 | 96% | 41.63 | 170 / 178 |
| esophagus | 41% | 638.85 | 594 / 1445 | 66% | 15.08 | 120 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 74.20 | 80 / 80 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.50 | 1 / 1 |
| adipose | 87% | 2313.35 | 1043 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 86% | 2124.22 | 693 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 24.14 | 24 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 26.58 | 34 / 45 |
| heart | 75% | 1673.19 | 647 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 54% | 891.83 | 725 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 32% | 469.43 | 77 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 16% | 321.68 | 149 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051066 | Biological process | dihydrobiopterin metabolic process |
| GO_0006559 | Biological process | L-phenylalanine catabolic process |
| GO_0006729 | Biological process | tetrahydrobiopterin biosynthetic process |
| GO_0006520 | Biological process | amino acid metabolic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0070402 | Molecular function | NADPH binding |
| GO_0070404 | Molecular function | NADH binding |
| GO_0004155 | Molecular function | 6,7-dihydropteridine reductase activity |
| GO_0009055 | Molecular function | electron transfer activity |
| Gene name | QDPR |
| Protein name | Quinoid dihydropteridine reductase Quinoid dihydropteridine reductase (cDNA FLJ55000, highly similar to Dihydropteridine reductase) Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) (Short chain dehydrogenase/reductase family 33C member 1) |
| Synonyms | hCG_39606 DHPR SDR33C1 |
| Description | FUNCTION: Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin. . |
| Accessions | ENST00000428702.6 [P09417-2] B7Z415 ENST00000281243.10 [P09417-1] ENST00000513615.5 D6RGG7 H0Y8F7 ENST00000508623.5 ENST00000505710.1 ENST00000507439.5 P09417 D6RHJ7 ENST00000514300.1 |