PYGM report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PYGM at tissue level.

III. Associated gene sets

GO_0005980Biological processglycogen catabolic process
GO_0005977Biological processglycogen metabolic process
GO_0005737Cellular componentcytoplasm
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0102499Molecular functionSHG alpha-glucan phosphorylase activity
GO_0008184Molecular functionglycogen phosphorylase activity
GO_0005515Molecular functionprotein binding
GO_0102250Molecular functionlinear malto-oligosaccharide phosphorylase activity
GO_0030170Molecular functionpyridoxal phosphate binding
GO_0000166Molecular functionnucleotide binding

IV. Literature review

[source]
Gene namePYGM
Protein nameGlycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)
Synonyms
DescriptionFUNCTION: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. .

FUNCTION: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. .

AccessionsP11217
ENST00000164139.4 [P11217-1]
ENST00000377432.7 [P11217-2]
A0A0M4FEM1