PYCR3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PYCR3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PYCR3 at tissue level.

III. Associated gene sets

GO_0055129Biological processL-proline biosynthetic process
GO_0005829Cellular componentcytosol
GO_0072686Cellular componentmitotic spindle
GO_0045171Cellular componentintercellular bridge
GO_0005515Molecular functionprotein binding
GO_0004735Molecular functionpyrroline-5-carboxylate reductase activity

IV. Literature review

[source]
Gene namePYCR3
Protein namePyrroline-5-carboxylate reductase 3 (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein)
Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein)
Pyrroline-5-carboxylate reductase 3
SynonymsPYCRL
DescriptionFUNCTION: Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. .

FUNCTION: Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. .

FUNCTION: Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. .

AccessionsENST00000634183.1
ENST00000220966.10
ENST00000495276.6 [Q53H96-1]
ENST00000462036.5
ENST00000633497.1
A0A0A0MQS1
ENST00000632107.1 [Q53H96-1]
ENST00000631620.1 [Q53H96-2]
Q53H96
ENST00000616663.2
F8WEI0
ENST00000447926.6
ENST00000433751.5 [Q53H96-2]
B5MD87
ENST00000633357.1
A0A087WTU2
ENST00000377579.7