Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 16 studies | 22% ± 6% | |
astrocyte | 12 studies | 32% ± 15% | |
endothelial cell | 9 studies | 32% ± 12% | |
oligodendrocyte precursor cell | 9 studies | 36% ± 17% | |
GABAergic neuron | 8 studies | 36% ± 19% | |
pericyte | 8 studies | 21% ± 6% | |
ciliated cell | 8 studies | 24% ± 7% | |
oligodendrocyte | 8 studies | 33% ± 13% | |
amacrine cell | 7 studies | 37% ± 14% | |
glutamatergic neuron | 6 studies | 39% ± 23% | |
adipocyte | 6 studies | 18% ± 3% | |
microglial cell | 6 studies | 29% ± 9% | |
myofibroblast cell | 5 studies | 20% ± 3% | |
retina horizontal cell | 5 studies | 32% ± 7% | |
mesothelial cell | 5 studies | 28% ± 11% | |
neuron | 5 studies | 40% ± 17% | |
interneuron | 5 studies | 37% ± 19% | |
retinal bipolar neuron | 4 studies | 34% ± 11% | |
retinal ganglion cell | 4 studies | 37% ± 16% | |
connective tissue cell | 4 studies | 24% ± 6% | |
epithelial cell | 4 studies | 35% ± 5% | |
Mueller cell | 4 studies | 24% ± 8% | |
ionocyte | 3 studies | 29% ± 4% | |
abnormal cell | 3 studies | 19% ± 3% | |
smooth muscle cell | 3 studies | 21% ± 4% | |
rod bipolar cell | 3 studies | 20% ± 2% | |
hepatocyte | 3 studies | 22% ± 7% | |
macrophage | 3 studies | 22% ± 1% | |
basal cell | 3 studies | 29% ± 10% | |
transit amplifying cell | 3 studies | 29% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 5508.60 | 2642 / 2642 | 100% | 33.75 | 703 / 705 |
skin | 100% | 2463.84 | 1807 / 1809 | 100% | 15.44 | 471 / 472 |
bladder | 100% | 3085.33 | 21 / 21 | 99% | 9.43 | 501 / 504 |
prostate | 100% | 3625.05 | 245 / 245 | 99% | 10.56 | 499 / 502 |
uterus | 100% | 4741.36 | 170 / 170 | 99% | 10.52 | 454 / 459 |
intestine | 100% | 3095.38 | 966 / 966 | 99% | 9.69 | 521 / 527 |
esophagus | 100% | 2790.67 | 1444 / 1445 | 99% | 8.95 | 181 / 183 |
thymus | 100% | 3491.65 | 653 / 653 | 99% | 9.70 | 597 / 605 |
breast | 100% | 3344.05 | 459 / 459 | 99% | 12.37 | 1103 / 1118 |
stomach | 99% | 2139.40 | 357 / 359 | 99% | 9.43 | 283 / 286 |
lung | 99% | 2776.45 | 575 / 578 | 98% | 8.56 | 1128 / 1155 |
adrenal gland | 99% | 2669.79 | 256 / 258 | 98% | 14.59 | 225 / 230 |
kidney | 100% | 2834.33 | 89 / 89 | 96% | 9.70 | 863 / 901 |
pancreas | 97% | 1467.01 | 318 / 328 | 98% | 10.60 | 175 / 178 |
liver | 99% | 2758.28 | 224 / 226 | 95% | 8.15 | 385 / 406 |
ovary | 100% | 5565.65 | 180 / 180 | 88% | 6.67 | 379 / 430 |
adipose | 100% | 3169.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 7.97 | 29 / 29 |
spleen | 100% | 3498.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 9.31 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.89 | 1 / 1 |
blood vessel | 100% | 3263.90 | 1332 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 16.40 | 79 / 80 |
heart | 96% | 1663.80 | 826 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 1243.76 | 760 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 43% | 715.80 | 398 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006325 | Biological process | chromatin organization |
GO_0006281 | Biological process | DNA repair |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0031491 | Molecular function | nucleosome binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PWWP3A |
Protein name | PWWP domain-containing DNA repair factor 3A Melanoma associated antigen (Mutated) 1, isoform CRA_b (cDNA: FLJ22283 fis, clone HRC03873) PWWP domain containing 3A, DNA repair factor MUM1 protein PWWP domain-containing DNA repair factor 3A (PWWP3A) (Mutated melanoma-associated antigen 1) (MUM-1) (PWWP domain-containing protein MUM1) (Protein expandere) |
Synonyms | hCG_2018726 EXPAND1 MUM1 |
Description | FUNCTION: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. . |
Accessions | Q9NPR8 ENST00000587460.6 K7END0 ENST00000591433.6 ENST00000592374.6 Q9H6H2 ENST00000591806.6 [Q2TAK8-1] A0A0D9SGJ8 ENST00000627377.1 J3KNX4 ENST00000652273.1 K7EP97 ENST00000588810.6 K7ES53 ENST00000591337.7 [Q2TAK8-1] ENST00000415183.7 [Q2TAK8-3] ENST00000591337 Q2TAK8 |