Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 8 studies | 31% ± 10% | |
plasmacytoid dendritic cell | 8 studies | 25% ± 7% | |
macrophage | 6 studies | 30% ± 18% | |
alveolar macrophage | 5 studies | 24% ± 5% | |
epithelial cell | 5 studies | 35% ± 16% | |
fibroblast | 4 studies | 22% ± 5% | |
dendritic cell | 4 studies | 32% ± 12% | |
classical monocyte | 3 studies | 21% ± 2% | |
conventional dendritic cell | 3 studies | 29% ± 9% | |
endothelial cell | 3 studies | 24% ± 8% | |
B cell | 3 studies | 20% ± 3% | |
natural killer cell | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 377.28 | 2642 / 2642 | 100% | 4.38 | 704 / 705 |
ovary | 100% | 241.59 | 180 / 180 | 99% | 4.37 | 427 / 430 |
esophagus | 100% | 290.44 | 1445 / 1445 | 99% | 2.78 | 181 / 183 |
prostate | 100% | 313.72 | 245 / 245 | 99% | 2.98 | 495 / 502 |
intestine | 100% | 277.26 | 966 / 966 | 98% | 3.94 | 519 / 527 |
stomach | 100% | 298.92 | 359 / 359 | 98% | 3.70 | 281 / 286 |
breast | 100% | 363.73 | 459 / 459 | 98% | 2.80 | 1091 / 1118 |
thymus | 100% | 311.73 | 653 / 653 | 97% | 2.02 | 585 / 605 |
lung | 100% | 352.67 | 578 / 578 | 96% | 2.47 | 1112 / 1155 |
pancreas | 100% | 234.16 | 328 / 328 | 94% | 1.81 | 167 / 178 |
uterus | 100% | 285.24 | 170 / 170 | 92% | 2.01 | 422 / 459 |
bladder | 100% | 249.52 | 21 / 21 | 92% | 2.75 | 463 / 504 |
kidney | 100% | 330.44 | 89 / 89 | 85% | 1.67 | 766 / 901 |
skin | 100% | 312.63 | 1808 / 1809 | 85% | 1.69 | 401 / 472 |
adrenal gland | 100% | 526.91 | 258 / 258 | 78% | 1.55 | 179 / 230 |
liver | 100% | 205.54 | 226 / 226 | 63% | 1.00 | 256 / 406 |
adipose | 100% | 344.89 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 2.42 | 29 / 29 |
spleen | 100% | 264.63 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.43 | 1 / 1 |
muscle | 100% | 240.38 | 801 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 251.15 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 143.10 | 821 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 93% | 2.00 | 74 / 80 |
tonsil | 0% | 0 | 0 / 0 | 89% | 1.71 | 40 / 45 |
peripheral blood | 75% | 156.69 | 697 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032049 | Biological process | cardiolipin biosynthetic process |
GO_2001242 | Biological process | regulation of intrinsic apoptotic signaling pathway |
GO_0005634 | Cellular component | nucleus |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008962 | Molecular function | phosphatidylglycerophosphatase activity |
GO_0004439 | Molecular function | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | PTPMT1 |
Protein name | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16, EC 3.1.3.48) Protein tyrosine phosphatase mitochondrial 1 |
Synonyms | MOSP PLIP PNAS-129 |
Description | FUNCTION: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (By similarity). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity). Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity). Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity). Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity). May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity . . |
Accessions | ENST00000326656.12 [Q8WUK0-2] E9PQM0 ENST00000534775.1 ENST00000326674.10 [Q8WUK0-1] ENST00000426530.2 [Q8WUK0-3] Q8WUK0 |