Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 25% ± 3% |
Insufficient scRNA-seq data for expression of PTGR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1214.50 | 2642 / 2642 | 64% | 1.01 | 450 / 705 |
thymus | 100% | 1381.42 | 653 / 653 | 46% | 0.68 | 279 / 605 |
breast | 100% | 931.19 | 459 / 459 | 31% | 0.47 | 341 / 1118 |
kidney | 100% | 1193.58 | 89 / 89 | 30% | 0.48 | 268 / 901 |
ovary | 100% | 931.17 | 180 / 180 | 29% | 0.41 | 126 / 430 |
prostate | 100% | 938.49 | 244 / 245 | 29% | 0.36 | 145 / 502 |
esophagus | 100% | 579.48 | 1442 / 1445 | 26% | 0.37 | 47 / 183 |
adrenal gland | 100% | 1512.41 | 258 / 258 | 17% | 0.21 | 38 / 230 |
lung | 99% | 613.35 | 571 / 578 | 15% | 0.26 | 173 / 1155 |
intestine | 100% | 728.74 | 966 / 966 | 10% | 0.15 | 55 / 527 |
stomach | 99% | 634.57 | 357 / 359 | 10% | 0.15 | 29 / 286 |
uterus | 99% | 616.42 | 169 / 170 | 10% | 0.15 | 46 / 459 |
skin | 99% | 751.79 | 1795 / 1809 | 10% | 0.13 | 45 / 472 |
bladder | 100% | 628.86 | 21 / 21 | 8% | 0.13 | 39 / 504 |
pancreas | 97% | 429.14 | 318 / 328 | 11% | 0.17 | 19 / 178 |
liver | 100% | 898.24 | 225 / 226 | 2% | 0.03 | 8 / 406 |
muscle | 100% | 1623.95 | 803 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 709.06 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 464.84 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 470.51 | 1317 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1565.00 | 825 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 21% | 164.02 | 196 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 0.22 | 12 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006693 | Biological process | prostaglandin metabolic process |
GO_0005737 | Cellular component | cytoplasm |
GO_0036132 | Molecular function | 13-prostaglandin reductase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0047522 | Molecular function | 15-oxoprostaglandin 13-oxidase activity |
Gene name | PTGR2 |
Protein name | Prostaglandin reductase 2 Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) |
Synonyms | ZADH1 |
Description | FUNCTION: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2 . Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). . |
Accessions | Q8N8N7 ENST00000553813.1 G3V2R9 ENST00000555228.5 [Q8N8N7-1] ENST00000555661.6 [Q8N8N7-1] ENST00000267568.8 [Q8N8N7-1] |