PTGFRN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PTGFRN at tissue level.

III. Associated gene sets

GO_0014905Biological processmyoblast fusion involved in skeletal muscle regeneration
GO_0034389Biological processlipid droplet organization
GO_0009986Cellular componentcell surface
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePTGFRN
Protein namePTGFRN protein
Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315)
SynonymsEWIF
FPRP
KIAA1436
CD9P1
DescriptionFUNCTION: Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity). .

AccessionsENST00000393203.3
A4QPA1
Q4QQP8
Q9P2B2
Q1WWL2