PSRC1 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	5 studies	29% ± 6%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2509.52	2632 / 2642	100%	85.22	704 / 705
esophagus	97%	828.27	1398 / 1445	82%	10.40	150 / 183
skin	73%	610.95	1329 / 1809	99%	36.64	467 / 472
uterus	74%	304.92	126 / 170	97%	24.95	446 / 459
lung	88%	500.66	511 / 578	79%	11.31	909 / 1155
ovary	64%	244.92	116 / 180	99%	25.19	424 / 430
intestine	67%	262.05	650 / 966	91%	14.85	481 / 527
bladder	67%	225.57	14 / 21	92%	15.92	463 / 504
stomach	46%	201.09	166 / 359	88%	12.51	252 / 286
breast	40%	136.93	185 / 459	92%	14.76	1033 / 1118
prostate	95%	542.16	233 / 245	37%	2.76	184 / 502
ureter	0%	0	0 / 0	100%	6.66	1 / 1
tonsil	0%	0	0 / 0	98%	21.45	44 / 45
eye	0%	0	0 / 0	98%	27.23	78 / 80
spleen	88%	341.24	211 / 241	0%	0	0 / 0
thymus	52%	161.26	341 / 653	29%	4.67	173 / 605
lymph node	0%	0	0 / 0	76%	6.83	22 / 29
liver	37%	160.14	84 / 226	38%	4.45	156 / 406
adrenal gland	26%	77.50	68 / 258	42%	4.26	97 / 230
pancreas	3%	8.93	9 / 328	62%	6.49	111 / 178
kidney	40%	137.64	36 / 89	24%	1.90	220 / 901
peripheral blood	60%	273.98	560 / 929	0%	0	0 / 0
blood vessel	55%	198.05	735 / 1335	0%	0	0 / 0
adipose	31%	95.99	373 / 1204	0%	0	0 / 0
heart	24%	71.44	204 / 861	0%	0	0 / 0
muscle	1%	1.82	6 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0031116	Biological process	positive regulation of microtubule polymerization
GO_0060236	Biological process	regulation of mitotic spindle organization
GO_0045737	Biological process	positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO_0051301	Biological process	cell division
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0007080	Biological process	mitotic metaphase chromosome alignment
GO_0001578	Biological process	microtubule bundle formation
GO_0030308	Biological process	negative regulation of cell growth
GO_0005876	Cellular component	spindle microtubule
GO_0030496	Cellular component	midbody
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0000922	Cellular component	spindle pole
GO_0005819	Cellular component	spindle
GO_0005737	Cellular component	cytoplasm
GO_0008017	Molecular function	microtubule binding
GO_0005515	Molecular function	protein binding

Gene name	PSRC1
Protein name	Proline/serine-rich coiled-coil protein 1 Proline and serine rich coiled-coil 1
Synonyms	FP3214 DDA3
Description	FUNCTION: Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. .
Accessions	ENST00000369909.7 [Q6PGN9-2] ENST00000369904.7 [Q6PGN9-3] S4R3S8 ENST00000474126.2 Q5T2Z0 ENST00000369907.7 [Q6PGN9-2] ENST00000429031.5 ENST00000418914.2 ENST00000369903.6 [Q6PGN9-2] ENST00000409138.6 [Q6PGN9-1] Q5T2Z1 Q6PGN9 ENST00000409267.5 [Q6PGN9-2]

PSRC1 report