Insufficient scRNA-seq data for expression of PRSS2 at single-cell level.
Insufficient scRNA-seq data for expression of PRSS2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 3302101.79 | 328 / 328 | 84% | 7915.19 | 149 / 178 |
| ovary | 70% | 342.71 | 126 / 180 | 84% | 57.50 | 362 / 430 |
| stomach | 83% | 1333.70 | 297 / 359 | 40% | 238.70 | 113 / 286 |
| intestine | 57% | 2098.56 | 551 / 966 | 42% | 400.10 | 219 / 527 |
| thymus | 44% | 252.15 | 290 / 653 | 46% | 38.13 | 279 / 605 |
| lung | 45% | 229.91 | 262 / 578 | 38% | 65.26 | 437 / 1155 |
| bladder | 57% | 188.71 | 12 / 21 | 26% | 90.79 | 130 / 504 |
| spleen | 79% | 458.60 | 191 / 241 | 0% | 0 | 0 / 0 |
| liver | 70% | 426.77 | 158 / 226 | 4% | 23.36 | 17 / 406 |
| uterus | 62% | 293.42 | 105 / 170 | 12% | 12.36 | 53 / 459 |
| esophagus | 54% | 387.43 | 779 / 1445 | 19% | 21.03 | 34 / 183 |
| adrenal gland | 70% | 335.11 | 180 / 258 | 0% | 0 | 0 / 230 |
| prostate | 57% | 427.80 | 139 / 245 | 2% | 0.24 | 9 / 502 |
| kidney | 54% | 212.87 | 48 / 89 | 3% | 0.39 | 25 / 901 |
| breast | 42% | 714.93 | 193 / 459 | 8% | 8.94 | 85 / 1118 |
| blood vessel | 43% | 730.88 | 577 / 1335 | 0% | 0 | 0 / 0 |
| skin | 40% | 255.17 | 730 / 1809 | 1% | 0.20 | 6 / 472 |
| peripheral blood | 40% | 209.08 | 370 / 929 | 0% | 0 | 0 / 0 |
| adipose | 40% | 1314.05 | 479 / 1204 | 0% | 0 | 0 / 0 |
| heart | 37% | 252.07 | 317 / 861 | 0% | 0 | 0 / 0 |
| brain | 33% | 160.16 | 863 / 2642 | 0% | 0.02 | 2 / 705 |
| muscle | 31% | 149.54 | 245 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.29 | 1 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.14 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019730 | Biological process | antimicrobial humoral response |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0045785 | Biological process | positive regulation of cell adhesion |
| GO_0006508 | Biological process | proteolysis |
| GO_0030574 | Biological process | collagen catabolic process |
| GO_0030307 | Biological process | positive regulation of cell growth |
| GO_0007586 | Biological process | digestion |
| GO_0035578 | Cellular component | azurophil granule lumen |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | PRSS2 |
| Protein name | Trypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II) trypsin (EC 3.4.21.4) |
| Synonyms | TRY8 TRY2 TRYP2 trypsinogen hCG_1770551 8 tcag7.1285 |
| Description | FUNCTION: In the ileum, may be involved in defensin processing, including DEFA5. . |
| Accessions | Q5NV56 ENST00000632998.1 ENST00000539842.6 Q3SY20 ENST00000633969.1 P07478 ENST00000632112.1 Q6PK75 A6XMV9 A0A0J9YYC8 |