PRSS2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PRSS2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRSS2 at tissue level.

III. Associated gene sets

GO_0019730Biological processantimicrobial humoral response
GO_0022617Biological processextracellular matrix disassembly
GO_0045785Biological processpositive regulation of cell adhesion
GO_0006508Biological processproteolysis
GO_0030574Biological processcollagen catabolic process
GO_0030307Biological processpositive regulation of cell growth
GO_0007586Biological processdigestion
GO_0035578Cellular componentazurophil granule lumen
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0008236Molecular functionserine-type peptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene namePRSS2
Protein nameTrypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II)
trypsin (EC 3.4.21.4)
SynonymsTRY8
TRY2
TRYP2
trypsinogen
hCG_1770551
8
tcag7.1285
DescriptionFUNCTION: In the ileum, may be involved in defensin processing, including DEFA5. .

AccessionsQ5NV56
ENST00000632998.1
ENST00000539842.6
Q3SY20
ENST00000633969.1
P07478
ENST00000632112.1
Q6PK75
A6XMV9
A0A0J9YYC8