I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| acinar cell | 3 studies | 93% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| acinar cell | 3 studies | 93% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 3 studies | 37% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 2647544.29 | 328 / 328 | 81% | 5321.36 | 144 / 178 |
| ovary | 66% | 341.17 | 119 / 180 | 82% | 27.27 | 353 / 430 |
| stomach | 87% | 1598.92 | 311 / 359 | 35% | 65.40 | 100 / 286 |
| thymus | 45% | 196.46 | 291 / 653 | 38% | 7.47 | 231 / 605 |
| spleen | 78% | 369.93 | 189 / 241 | 0% | 0 | 0 / 0 |
| intestine | 52% | 281.25 | 506 / 966 | 23% | 119.38 | 123 / 527 |
| bladder | 57% | 123.95 | 12 / 21 | 18% | 17.58 | 92 / 504 |
| adrenal gland | 71% | 267.49 | 182 / 258 | 4% | 0.56 | 10 / 230 |
| liver | 70% | 390.94 | 158 / 226 | 4% | 14.92 | 18 / 406 |
| esophagus | 55% | 346.73 | 789 / 1445 | 18% | 4.15 | 33 / 183 |
| uterus | 62% | 228.21 | 106 / 170 | 8% | 1.92 | 37 / 459 |
| lung | 44% | 183.32 | 254 / 578 | 21% | 6.13 | 242 / 1155 |
| kidney | 61% | 220.21 | 54 / 89 | 4% | 0.35 | 34 / 901 |
| prostate | 56% | 371.07 | 138 / 245 | 2% | 0.13 | 8 / 502 |
| breast | 42% | 711.46 | 195 / 459 | 8% | 2.04 | 95 / 1118 |
| blood vessel | 44% | 406.05 | 583 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 41% | 935.00 | 498 / 1204 | 0% | 0 | 0 / 0 |
| skin | 40% | 240.16 | 732 / 1809 | 0% | 0.02 | 2 / 472 |
| peripheral blood | 39% | 162.28 | 360 / 929 | 0% | 0 | 0 / 0 |
| heart | 38% | 220.07 | 325 / 861 | 0% | 0 | 0 / 0 |
| muscle | 32% | 136.04 | 260 / 803 | 0% | 0 | 0 / 0 |
| brain | 31% | 131.99 | 815 / 2642 | 0% | 0.01 | 3 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.41 | 3 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.09 | 1 / 45 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0006508 | Biological process | proteolysis |
| GO_0007586 | Biological process | digestion |
| GO_0005615 | Cellular component | extracellular space |
| GO_0072562 | Cellular component | blood microparticle |
| GO_0005576 | Cellular component | extracellular region |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | PRSS1 |
| Protein name | Serine protease 1 Protease serine 1 (Serine protease 1) Trypsin I Protease serine 1 (EC 3.4.21.4) Nonfunctional trypsin 1 (EC 3.4.21.4) trypsin (EC 3.4.21.4) Cationic trypsinogen (EC 3.4.21.4) Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsinogen) (Pretrypsinogen I) (Trypsin I) (Trypsin-1) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2] |
| Synonyms | TRY1 TRYP1 TRP1 |
| Description | FUNCTION: Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. . |
| Accessions | ENST00000492062.1 Q53ZF3 Q7Z5P3 ENST00000633149.1 P07477 Q7Z445 Q86W19 Q53ZX9 Q86W18 Q3SY19 Q7Z5Y9 Q45KI0 ENST00000616256.4 Q53ZX7 ENST00000486171.5 ENST00000622109.1 Q53ZV8 ENST00000633245.1 A6XGL3 ENST00000311737.12 Q53ZX8 Q86W20 Q86W17 H0Y8D1 E7EQ64 |
