PRR14 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRR14 at tissue level.

III. Associated gene sets

GO_0007517Biological processmuscle organ development
GO_0005652Cellular componentnuclear lamina
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePRR14
Protein nameProline-rich protein 14
Proline rich 14
PRR14 protein
Synonyms
DescriptionFUNCTION: Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha . Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit . Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha . Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 . .

AccessionsH3BQL8
H3BND2
ENST00000542965.2
ENST00000569864.5
ENST00000568754.5
Q9BWN1
ENST00000300835.9
Q96D88