I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 19% ± 3% | |
| epithelial cell | 3 studies | 25% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 19% ± 3% | |
| epithelial cell | 3 studies | 25% ± 6% |
Insufficient scRNA-seq data for expression of PRR14 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3241.85 | 1445 / 1445 | 100% | 39.28 | 183 / 183 |
| ovary | 100% | 3441.01 | 180 / 180 | 100% | 44.46 | 430 / 430 |
| skin | 100% | 2762.25 | 1809 / 1809 | 100% | 40.82 | 472 / 472 |
| thymus | 100% | 3529.59 | 653 / 653 | 100% | 38.95 | 605 / 605 |
| uterus | 100% | 4153.99 | 170 / 170 | 100% | 42.61 | 459 / 459 |
| liver | 100% | 1610.06 | 226 / 226 | 100% | 21.03 | 405 / 406 |
| brain | 100% | 2269.68 | 2632 / 2642 | 100% | 50.56 | 705 / 705 |
| intestine | 100% | 3655.04 | 966 / 966 | 100% | 38.66 | 525 / 527 |
| prostate | 100% | 3879.46 | 245 / 245 | 100% | 33.89 | 500 / 502 |
| adrenal gland | 100% | 2672.60 | 258 / 258 | 100% | 30.52 | 229 / 230 |
| lung | 100% | 3555.74 | 578 / 578 | 99% | 34.60 | 1149 / 1155 |
| pancreas | 100% | 2022.20 | 328 / 328 | 99% | 38.29 | 177 / 178 |
| stomach | 100% | 2858.21 | 359 / 359 | 99% | 39.65 | 284 / 286 |
| kidney | 100% | 2888.96 | 89 / 89 | 99% | 31.87 | 894 / 901 |
| breast | 100% | 2850.90 | 459 / 459 | 99% | 46.32 | 1108 / 1118 |
| bladder | 100% | 3252.29 | 21 / 21 | 99% | 41.27 | 499 / 504 |
| adipose | 100% | 2695.96 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 25.52 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 46.61 | 29 / 29 |
| spleen | 100% | 4897.27 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 36.55 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.35 | 1 / 1 |
| blood vessel | 100% | 3098.20 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 4150.64 | 926 / 929 | 0% | 0 | 0 / 0 |
| heart | 100% | 1420.33 | 857 / 861 | 0% | 0 | 0 / 0 |
| muscle | 97% | 1086.39 | 779 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007517 | Biological process | muscle organ development |
| GO_0005652 | Cellular component | nuclear lamina |
| GO_0005694 | Cellular component | chromosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PRR14 |
| Protein name | Proline-rich protein 14 Proline rich 14 PRR14 protein |
| Synonyms | |
| Description | FUNCTION: Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha . Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit . Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha . Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 . . |
| Accessions | H3BQL8 H3BND2 ENST00000542965.2 ENST00000569864.5 ENST00000568754.5 Q9BWN1 ENST00000300835.9 Q96D88 |
