PROZ report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PROZ at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PROZ at tissue level.

III. Associated gene sets

GO_0007596Biological processblood coagulation
GO_0006508Biological processproteolysis
GO_0005615Cellular componentextracellular space
GO_0005796Cellular componentGolgi lumen
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0070062Cellular componentextracellular exosome
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene namePROZ
Protein nameVitamin K-dependent protein Z
Vitamin K-dependent protein Z variant 1
Synonyms
DescriptionFUNCTION: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.

AccessionsENST00000375547.7 [P22891-1]
ENST00000342783.5 [P22891-2]
B0YJC6
P22891