PRMT8 | OmnibusX

Name	Number of supported studies	Average coverage
brain	4 studies	43% ± 21%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	87%	1365.07	2299 / 2642	54%	2.50	383 / 705
thymus	0%	0.96	3 / 653	38%	3.48	228 / 605
lung	20%	49.09	114 / 578	12%	0.40	140 / 1155
heart	14%	28.20	119 / 861	0%	0	0 / 0
adrenal gland	0%	0.79	1 / 258	10%	0.54	23 / 230
kidney	3%	6.83	3 / 89	5%	0.10	45 / 901
pancreas	2%	4.65	8 / 328	1%	0.03	2 / 178
uterus	1%	1.74	2 / 170	2%	0.04	8 / 459
breast	0%	0	0 / 459	3%	0.13	31 / 1118
esophagus	0%	0	0 / 1445	3%	0.07	5 / 183
ovary	0%	0	0 / 180	2%	0.05	8 / 430
bladder	0%	0	0 / 21	2%	0.04	9 / 504
eye	0%	0	0 / 0	1%	0.04	1 / 80
intestine	0%	0	0 / 966	1%	0.03	5 / 527
skin	0%	0	0 / 1809	1%	0.04	4 / 472
stomach	0%	0	0 / 359	1%	0.01	2 / 286
liver	0%	0	0 / 226	0%	0.00	1 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006338	Biological process	chromatin remodeling
GO_0006479	Biological process	protein methylation
GO_0051260	Biological process	protein homooligomerization
GO_0018216	Biological process	peptidyl-arginine methylation
GO_0019919	Biological process	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0005634	Cellular component	nucleus
GO_1904047	Molecular function	S-adenosyl-L-methionine binding
GO_0019899	Molecular function	enzyme binding
GO_0042803	Molecular function	protein homodimerization activity
GO_0042054	Molecular function	histone methyltransferase activity
GO_0035242	Molecular function	protein-arginine omega-N asymmetric methyltransferase activity
GO_0140939	Molecular function	histone H4 methyltransferase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0008757	Molecular function	S-adenosylmethionine-dependent methyltransferase activity
GO_0035241	Molecular function	protein-arginine omega-N monomethyltransferase activity

Gene name	PRMT8
Protein name	Protein arginine N-methyltransferase 8 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) Protein arginine methyltransferase 8, isoform CRA_b (cDNA: FLJ23133 fis, clone LNG08560) Arginine methyltransferase 8 isoform 4
Synonyms	HRMT1L4 hCG_24446 HRMT1L3
Description	FUNCTION: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer . Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS . .
Accessions	Q9H5R7 Q9NR22 A0A0G2UEQ4 ENST00000452611.6 [Q9NR22-2] ENST00000382622.4 [Q9NR22-1]

PRMT8 report