PRDM7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PRDM7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRDM7 at tissue level.

III. Associated gene sets

GO_0010845Biological processpositive regulation of reciprocal meiotic recombination
GO_0010468Biological processregulation of gene expression
GO_0032259Biological processmethylation
GO_0006338Biological processchromatin remodeling
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005694Cellular componentchromosome
GO_0005634Cellular componentnucleus
GO_0010844Molecular functionrecombination hotspot binding
GO_0042800Molecular functionhistone H3K4 methyltransferase activity
GO_0046975Molecular functionhistone H3K36 methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePRDM7
Protein namePR/SET domain 7 (PRDM7 long isoform, variant 2)
PR/SET domain 7
Histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.-) (PR domain zinc finger protein 7) (PR domain-containing protein 7) ([histone H3]-lysine4 N-methyltransferase PRDM7)
SynonymsPFM4
PRDM7_V2
DescriptionFUNCTION: Histone methyltransferase that selectively methylates 'Lys-4' of dimethylated histone H3 (H3K4me2) to produce trimethylated 'Lys-4' histone H3 (H3K4me3). May play a role in epigenetic regulation of gene expression by defining an active chromatin state. .

AccessionsENST00000568473.5
ENST00000564210.2
A4Q9G9
Q9NQW5
ENST00000449207.8 [Q9NQW5-3]
H3BUJ3