PPY report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PPY at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PPY at tissue level.

III. Associated gene sets

GO_0007631Biological processfeeding behavior
GO_0007218Biological processneuropeptide signaling pathway
GO_0009306Biological processprotein secretion
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005737Cellular componentcytoplasm
GO_0005179Molecular functionhormone activity
GO_0005515Molecular functionprotein binding
GO_0005184Molecular functionneuropeptide hormone activity
GO_0031841Molecular functionneuropeptide Y receptor binding
GO_0001664Molecular functionG protein-coupled receptor binding

IV. Literature review

[source]
Gene namePPY
Protein namePancreatic polypeptide
Pancreatic polypeptide prohormone (PH) (Pancreatic polypeptide Y) (Obinepitide) [Cleaved into: Pancreatic polypeptide (HPP) (PP); Pancreatic icosapeptide (PI)]
SynonymsPNP
DescriptionFUNCTION: [Pancreatic polypeptide]: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2. .

FUNCTION: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2. .

FUNCTION: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2. .

AccessionsENST00000587006.2
ENST00000591228.4 [P01298-1]
ENST00000591703.5
K7EKP2
A0A0U1RRD5
ENST00000225992.8 [P01298-1]
ENST00000587070.5
K7EML0
P01298