PPP3R2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PPP3R2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PPP3R2 at tissue level.

III. Associated gene sets

GO_0070886Biological processpositive regulation of calcineurin-NFAT signaling cascade
GO_1905665Biological processpositive regulation of calcium ion import across plasma membrane
GO_0097720Biological processcalcineurin-mediated signaling
GO_0006470Biological processprotein dephosphorylation
GO_1905949Biological processnegative regulation of calcium ion import across plasma membrane
GO_0007341Biological processpenetration of zona pellucida
GO_0005829Cellular componentcytosol
GO_0005955Cellular componentcalcineurin complex
GO_0097226Cellular componentsperm mitochondrial sheath
GO_0008287Cellular componentprotein serine/threonine phosphatase complex
GO_0005739Cellular componentmitochondrion
GO_0019902Molecular functionphosphatase binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0008597Molecular functioncalcium-dependent protein serine/threonine phosphatase regulator activity

IV. Literature review

[source]
Gene namePPP3R2
Protein nameCalcineurin subunit B type 2 (Calcineurin B-like protein) (CBLP) (Calcineurin BII) (CNBII) (PPP3R1-like) (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform)
Protein phosphatase 3 regulatory subunit B, beta
SynonymsPPP3RL
CBLP
DescriptionFUNCTION: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. .

AccessionsA0A1B0GUC7
ENST00000636434.1
ENST00000374806.2
Q96LZ3