PPP1R3C report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PPP1R3C at tissue level.

III. Associated gene sets

GO_0005979Biological processregulation of glycogen biosynthetic process
GO_0005978Biological processglycogen biosynthetic process
GO_0005977Biological processglycogen metabolic process
GO_0000164Cellular componentprotein phosphatase type 1 complex
GO_0005829Cellular componentcytosol
GO_2001069Molecular functionglycogen binding
GO_0060090Molecular functionmolecular adaptor activity
GO_0008157Molecular functionprotein phosphatase 1 binding
GO_0005515Molecular functionprotein binding
GO_0019903Molecular functionprotein phosphatase binding
GO_0004722Molecular functionprotein serine/threonine phosphatase activity

IV. Literature review

[source]
Gene namePPP1R3C
Protein nameProtein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)
SynonymsPPP1R5
DescriptionFUNCTION: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. .

AccessionsQ9UQK1
ENST00000238994.6