Name | Number of supported studies | Average coverage | |
---|---|---|---|
hepatocyte | 4 studies | 29% ± 11% | |
pancreatic A cell | 3 studies | 22% ± 8% | |
epithelial cell | 3 studies | 35% ± 13% |
Insufficient scRNA-seq data for expression of PPP1R3B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 3725.44 | 243 / 245 | 99% | 32.28 | 498 / 502 |
breast | 100% | 4548.69 | 458 / 459 | 98% | 44.06 | 1097 / 1118 |
thymus | 100% | 2445.45 | 650 / 653 | 96% | 51.81 | 579 / 605 |
lung | 98% | 2483.31 | 568 / 578 | 97% | 31.53 | 1119 / 1155 |
liver | 100% | 11671.42 | 226 / 226 | 93% | 37.59 | 376 / 406 |
stomach | 98% | 2233.08 | 351 / 359 | 93% | 22.96 | 266 / 286 |
intestine | 98% | 3024.22 | 946 / 966 | 93% | 19.21 | 488 / 527 |
uterus | 100% | 4654.16 | 170 / 170 | 89% | 25.08 | 409 / 459 |
skin | 98% | 2753.57 | 1769 / 1809 | 91% | 25.16 | 430 / 472 |
esophagus | 99% | 3467.16 | 1428 / 1445 | 90% | 26.39 | 164 / 183 |
bladder | 100% | 7210.62 | 21 / 21 | 86% | 20.00 | 432 / 504 |
kidney | 91% | 1755.92 | 81 / 89 | 94% | 52.20 | 850 / 901 |
adrenal gland | 86% | 1676.50 | 221 / 258 | 93% | 35.05 | 213 / 230 |
ovary | 87% | 1499.23 | 156 / 180 | 40% | 5.19 | 171 / 430 |
pancreas | 21% | 256.51 | 69 / 328 | 95% | 26.00 | 169 / 178 |
blood vessel | 100% | 8602.57 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 9002.67 | 803 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 5222.68 | 1199 / 1204 | 0% | 0 | 0 / 0 |
spleen | 98% | 2064.32 | 237 / 241 | 0% | 0 | 0 / 0 |
heart | 96% | 5074.48 | 826 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 87% | 6151.51 | 806 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 13.71 | 37 / 45 |
eye | 0% | 0 | 0 / 0 | 75% | 17.44 | 60 / 80 |
brain | 4% | 55.78 | 113 / 2642 | 46% | 6.89 | 325 / 705 |
lymph node | 0% | 0 | 0 / 0 | 41% | 4.52 | 12 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0005979 | Biological process | regulation of glycogen biosynthetic process |
GO_0005981 | Biological process | regulation of glycogen catabolic process |
GO_0005977 | Biological process | glycogen metabolic process |
GO_0000164 | Cellular component | protein phosphatase type 1 complex |
GO_0042587 | Cellular component | glycogen granule |
GO_2001069 | Molecular function | glycogen binding |
GO_0008157 | Molecular function | protein phosphatase 1 binding |
GO_0019888 | Molecular function | protein phosphatase regulator activity |
GO_0005515 | Molecular function | protein binding |
GO_0050196 | Molecular function | [phosphorylase] phosphatase activity |
Gene name | PPP1R3B |
Protein name | Protein phosphatase 1 regulatory subunit 3B (Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL) (Protein phosphatase 1 regulatory subunit 4) (PP1 subunit R4) (Protein phosphatase 1 subunit GL) (PTG) |
Synonyms | PPP1R4 |
Description | FUNCTION: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). . |
Accessions | ENST00000519699.1 ENST00000310455.4 ENST00000644687.1 Q86XI6 ENST00000645121.2 |