Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| kidney loop of Henle epithelial cell | 5 studies | 42% ± 9% | |
| pancreatic A cell | 4 studies | 56% ± 21% | |
| type B pancreatic cell | 4 studies | 70% ± 9% | |
| retina horizontal cell | 4 studies | 45% ± 16% | |
| pancreatic D cell | 3 studies | 53% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 4 studies | 43% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 90% | 5185.11 | 204 / 226 | 83% | 46.06 | 336 / 406 |
| brain | 72% | 4267.20 | 1908 / 2642 | 79% | 17.58 | 560 / 705 |
| kidney | 91% | 6494.92 | 81 / 89 | 60% | 29.56 | 538 / 901 |
| breast | 82% | 12670.64 | 377 / 459 | 53% | 9.47 | 591 / 1118 |
| muscle | 100% | 31220.16 | 803 / 803 | 0% | 0 | 0 / 0 |
| adipose | 96% | 15203.88 | 1152 / 1204 | 0% | 0 | 0 / 0 |
| heart | 89% | 5387.71 | 766 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 4% | 80.84 | 14 / 328 | 52% | 16.35 | 93 / 178 |
| intestine | 43% | 1305.25 | 420 / 966 | 9% | 1.14 | 45 / 527 |
| blood vessel | 48% | 1242.05 | 637 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 33% | 1735.54 | 119 / 359 | 14% | 1.46 | 39 / 286 |
| ovary | 4% | 60.68 | 7 / 180 | 34% | 3.88 | 146 / 430 |
| prostate | 13% | 279.18 | 32 / 245 | 25% | 1.59 | 123 / 502 |
| esophagus | 22% | 667.01 | 323 / 1445 | 2% | 0.31 | 4 / 183 |
| uterus | 0% | 0 | 0 / 170 | 20% | 6.01 | 91 / 459 |
| skin | 6% | 146.36 | 100 / 1809 | 7% | 0.81 | 34 / 472 |
| adrenal gland | 2% | 37.16 | 4 / 258 | 9% | 1.77 | 21 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.73 | 3 / 29 |
| thymus | 1% | 32.54 | 7 / 653 | 7% | 0.47 | 42 / 605 |
| bladder | 0% | 0 | 0 / 21 | 7% | 0.71 | 35 / 504 |
| lung | 0% | 5.43 | 1 / 578 | 6% | 0.68 | 74 / 1155 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.35 | 4 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.22 | 2 / 45 |
| peripheral blood | 2% | 38.30 | 16 / 929 | 0% | 0 | 0 / 0 |
| spleen | 0% | 5.99 | 1 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0005977 | Biological process | glycogen metabolic process |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| GO_0004865 | Molecular function | protein serine/threonine phosphatase inhibitor activity |
| Gene name | PPP1R1A |
| Protein name | Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1) Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) |
| Synonyms | IPP1 |
| Description | FUNCTION: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. FUNCTION: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. . FUNCTION: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. . FUNCTION: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. . |
| Accessions | ENST00000553113.5 R4GMQ8 H0YIU4 F8VR76 ENST00000547826.2 ENST00000257905.13 ENST00000547431.5 Q13522 |
