Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 14 studies | 41% ± 20% | |
| glutamatergic neuron | 13 studies | 60% ± 27% | |
| GABAergic neuron | 11 studies | 46% ± 23% | |
| endothelial cell | 11 studies | 31% ± 16% | |
| oligodendrocyte precursor cell | 11 studies | 32% ± 10% | |
| pericyte | 10 studies | 28% ± 15% | |
| macrophage | 9 studies | 32% ± 9% | |
| microglial cell | 9 studies | 28% ± 14% | |
| adipocyte | 9 studies | 34% ± 12% | |
| oligodendrocyte | 9 studies | 25% ± 14% | |
| interneuron | 7 studies | 57% ± 24% | |
| neuron | 6 studies | 44% ± 11% | |
| retinal ganglion cell | 6 studies | 33% ± 17% | |
| smooth muscle cell | 6 studies | 40% ± 8% | |
| club cell | 5 studies | 23% ± 8% | |
| cardiac muscle cell | 5 studies | 49% ± 16% | |
| type I pneumocyte | 5 studies | 25% ± 3% | |
| hepatocyte | 4 studies | 43% ± 24% | |
| epithelial cell | 4 studies | 31% ± 19% | |
| granule cell | 4 studies | 34% ± 8% | |
| retinal bipolar neuron | 4 studies | 37% ± 19% | |
| dendritic cell | 4 studies | 19% ± 2% | |
| retinal cone cell | 4 studies | 52% ± 13% | |
| respiratory goblet cell | 4 studies | 28% ± 10% | |
| myeloid cell | 4 studies | 29% ± 8% | |
| monocyte | 4 studies | 29% ± 9% | |
| GABAergic interneuron | 3 studies | 42% ± 7% | |
| non-classical monocyte | 3 studies | 19% ± 2% | |
| GABAergic amacrine cell | 3 studies | 42% ± 11% | |
| ON-bipolar cell | 3 studies | 49% ± 19% | |
| amacrine cell | 3 studies | 39% ± 5% | |
| glycinergic amacrine cell | 3 studies | 34% ± 5% | |
| rod bipolar cell | 3 studies | 57% ± 21% | |
| fibroblast | 3 studies | 25% ± 9% | |
| retinal pigment epithelial cell | 3 studies | 20% ± 2% | |
| neural progenitor cell | 3 studies | 41% ± 8% | |
| ependymal cell | 3 studies | 37% ± 22% | |
| natural killer cell | 3 studies | 27% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 3013.77 | 2604 / 2642 | 100% | 23.28 | 704 / 705 |
| thymus | 100% | 2017.29 | 651 / 653 | 93% | 8.05 | 565 / 605 |
| adrenal gland | 98% | 1779.06 | 252 / 258 | 93% | 12.37 | 214 / 230 |
| esophagus | 99% | 2574.73 | 1436 / 1445 | 89% | 9.14 | 163 / 183 |
| breast | 98% | 1636.20 | 451 / 459 | 88% | 5.19 | 987 / 1118 |
| prostate | 97% | 1473.10 | 237 / 245 | 89% | 5.26 | 449 / 502 |
| stomach | 99% | 2187.65 | 357 / 359 | 85% | 6.09 | 243 / 286 |
| intestine | 98% | 2197.78 | 951 / 966 | 80% | 4.40 | 422 / 527 |
| bladder | 100% | 5134.38 | 21 / 21 | 78% | 5.36 | 393 / 504 |
| kidney | 87% | 764.07 | 77 / 89 | 88% | 9.64 | 790 / 901 |
| pancreas | 81% | 768.19 | 266 / 328 | 92% | 5.89 | 164 / 178 |
| lung | 97% | 1468.52 | 563 / 578 | 75% | 6.10 | 867 / 1155 |
| uterus | 99% | 1482.30 | 168 / 170 | 72% | 5.63 | 330 / 459 |
| liver | 65% | 591.09 | 148 / 226 | 62% | 2.94 | 252 / 406 |
| skin | 75% | 1868.04 | 1348 / 1809 | 47% | 2.04 | 222 / 472 |
| ovary | 85% | 811.41 | 153 / 180 | 27% | 1.37 | 115 / 430 |
| muscle | 100% | 5735.17 | 803 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 2534.30 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 95% | 2018.57 | 1143 / 1204 | 0% | 0 | 0 / 0 |
| heart | 91% | 1767.82 | 780 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 78% | 6.89 | 35 / 45 |
| spleen | 76% | 576.25 | 182 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 3.55 | 19 / 29 |
| peripheral blood | 20% | 164.00 | 190 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 15% | 0.45 | 12 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030148 | Biological process | sphingolipid biosynthetic process |
| GO_0007178 | Biological process | cell surface receptor protein serine/threonine kinase signaling pathway |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0000165 | Biological process | MAPK cascade |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0017018 | Molecular function | myosin phosphatase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
| Gene name | PPM1L |
| Protein name | Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon) |
| Synonyms | PP2CE |
| Description | FUNCTION: Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. . |
| Accessions | Q5SGD2 ENST00000295839.9 [Q5SGD2-3] ENST00000464260.5 [Q5SGD2-2] ENST00000497343.5 [Q5SGD2-4] ENST00000498165.6 [Q5SGD2-1] |