POMGNT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016266Biological processO-glycan processing
GO_0071711Biological processbasement membrane organization
GO_0007605Biological processsensory perception of sound
GO_0010467Biological processgene expression
GO_0021542Biological processdentate gyrus development
GO_0051674Biological processlocalization of cell
GO_0042552Biological processmyelination
GO_0006493Biological processprotein O-linked glycosylation
GO_0150103Biological processreactive gliosis
GO_0035269Biological processprotein O-linked mannosylation
GO_0000139Cellular componentGolgi membrane
GO_0016020Cellular componentmembrane
GO_0030145Molecular functionmanganese ion binding
GO_0008375Molecular functionacetylglucosaminyltransferase activity
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding
GO_0047223Molecular functionbeta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity

IV. Literature review

[source]
Gene namePOMGNT1
Protein nameProtein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) (Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1)
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase (POMGnT1) (EC 2.4.1.-)
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)
Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
SynonymsDKFZp761B182
UNQ746/PRO1475
MGAT1.2
DescriptionFUNCTION: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity. .

FUNCTION: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. .

FUNCTION: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. .

FUNCTION: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. .

FUNCTION: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. .

AccessionsA0A8I5KQE4
A0A8I5KPT5
A0A8I5KVA5
ENST00000685230.1
ENST00000687149.1
ENST00000686379.1
ENST00000686737.1 [Q8WZA1-1]
ENST00000690678.1 [Q8WZA1-1]
Q68CV6
A0A8I5KR25
A0A8I5KTS5
ENST00000396420
ENST00000692322.1
ENST00000692369.1
ENST00000371984.8 [Q8WZA1-1]
Q8WZA1
A0A8I5QJA9
ENST00000687683.1 [Q8WZA1-1]
ENST00000685444.1
ENST00000692635.1
ENST00000693218.1
ENST00000691243.1
ENST00000691209.1
ENST00000689756.1
ENST00000396420.8 [Q8WZA1-1]
ENST00000371992.1 [Q8WZA1-2]
A0A8I5QJV3
A0A8I5KNB7
ENST00000687197.1
ENST00000688608.1
A0A8I5KSR6