POGLUT3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of POGLUT3 at tissue level.

III. Associated gene sets

GO_0018242Biological processprotein O-linked glycosylation via serine
GO_0005575Cellular componentcellular_component
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0012505Cellular componentendomembrane system
GO_0046527Molecular functionglucosyltransferase activity
GO_0140562Molecular functionEGF-domain serine xylosyltransferase activity
GO_0035251Molecular functionUDP-glucosyltransferase activity
GO_0035252Molecular functionUDP-xylosyltransferase activity
GO_0140561Molecular functionEGF-domain serine glucosyltransferase activity

IV. Literature review

[source]
Gene namePOGLUT3
Protein nameProtein O-glucosyltransferase 3 (EC 2.4.1.-) (KDEL motif-containing protein 2) (Protein O-xylosyltransferase POGLUT3) (EC 2.4.2.-)
Protein O-glucosyltransferase 3
SynonymsKDELC2
UNQ1904/PRO4350
DescriptionFUNCTION: Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C . Can also catalyze the transfer of xylose from UDP-xylose but less efficiently . Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1 . May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway . .

AccessionsENST00000706524.1
ENST00000434945.6 [Q7Z4H8-2]
ENST00000323468.10 [Q7Z4H8-1]
ENST00000706523.1
H0YEM3
ENST00000530529.5 [Q7Z4H8-3]
Q7Z4H8
ENST00000530318.1
A0A9L9PX09
A0A9L9PY40