POC1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0001895Biological processretina homeostasis
GO_0008283Biological processcell population proliferation
GO_0007099Biological processcentriole replication
GO_0005814Cellular componentcentriole
GO_0005813Cellular componentcentrosome
GO_0036064Cellular componentciliary basal body
GO_0000922Cellular componentspindle pole
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePOC1B
Protein namePOC1 centriolar protein B
POC1 centriolar protein homolog B
POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B)
SynonymsTUWD12
WDR51B
hCG_27606
DescriptionFUNCTION: Plays an important role in centriole assembly and/or stability and ciliogenesis . Involved in early steps of centriole duplication, as well as in the later steps of centriole length control . Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation . Required for primary cilia formation, ciliary length and also cell proliferation . Required for retinal integrity . .

AccessionsENST00000313546.8 [Q8TC44-1]
ENST00000547496.5
ENST00000393179.8
F8VPF1
ENST00000547274.5
ENST00000549504.1
F8VX21
F8VV91
ENST00000549035.1 [Q8TC44-2]
Q8IU52
ENST00000546830.1
ENST00000548715.5
Q8TC44