PNMA3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
glutamatergic neuron	5 studies	40% ± 22%	Explore
neuron	3 studies	17% ± 0%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	5 studies	28% ± 17%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	96%	3753.67	2533 / 2642	88%	15.27	619 / 705
kidney	53%	348.00	47 / 89	59%	6.89	530 / 901
thymus	64%	372.69	421 / 653	36%	2.08	220 / 605
eye	0%	0	0 / 0	100%	103.52	80 / 80
adrenal gland	44%	246.48	114 / 258	52%	8.74	119 / 230
ovary	17%	87.32	30 / 180	76%	9.30	326 / 430
spleen	91%	780.89	220 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	55%	2.23	16 / 29
skin	6%	23.32	101 / 1809	35%	4.68	166 / 472
uterus	6%	39.79	11 / 170	32%	5.11	146 / 459
tonsil	0%	0	0 / 0	33%	2.14	15 / 45
lung	8%	36.65	45 / 578	24%	1.93	277 / 1155
liver	1%	3.93	2 / 226	24%	4.44	97 / 406
peripheral blood	25%	113.76	228 / 929	0%	0	0 / 0
heart	24%	100.45	203 / 861	0%	0	0 / 0
intestine	18%	160.56	172 / 966	4%	0.44	22 / 527
prostate	13%	53.19	32 / 245	8%	0.29	38 / 502
bladder	10%	31.24	2 / 21	10%	0.77	52 / 504
breast	2%	8.23	11 / 459	13%	0.88	141 / 1118
pancreas	0%	0.91	1 / 328	13%	0.76	24 / 178
stomach	5%	21.42	18 / 359	5%	0.65	14 / 286
esophagus	2%	6.73	24 / 1445	7%	0.53	12 / 183
adipose	3%	12.90	34 / 1204	0%	0	0 / 0
blood vessel	1%	7.52	20 / 1335	0%	0	0 / 0
muscle	0%	0.35	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1