PLXNB3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLXNB3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	4570.69	2598 / 2642	98%	45.65	693 / 705
prostate	99%	3075.76	242 / 245	95%	15.98	478 / 502
adrenal gland	100%	4181.22	258 / 258	88%	24.34	202 / 230
skin	78%	1079.46	1409 / 1809	94%	28.23	444 / 472
breast	94%	3007.47	431 / 459	77%	7.75	860 / 1118
esophagus	90%	3488.71	1305 / 1445	74%	12.13	135 / 183
uterus	98%	4388.26	166 / 170	62%	6.22	285 / 459
bladder	95%	3664.71	20 / 21	56%	7.11	280 / 504
pancreas	30%	307.45	97 / 328	70%	7.06	124 / 178
intestine	78%	6325.53	751 / 966	20%	1.85	107 / 527
lung	25%	256.38	144 / 578	71%	8.91	821 / 1155
eye	0%	0	0 / 0	86%	7.29	69 / 80
stomach	59%	2155.76	213 / 359	25%	2.34	72 / 286
blood vessel	84%	1900.58	1128 / 1335	0%	0	0 / 0
adipose	75%	1874.91	899 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	60%	4.43	27 / 45
heart	41%	554.07	357 / 861	0%	0	0 / 0
ovary	11%	185.73	20 / 180	13%	0.99	57 / 430
liver	0%	3.96	1 / 226	16%	2.66	64 / 406
kidney	2%	17.44	2 / 89	8%	0.70	75 / 901
thymus	6%	60.32	42 / 653	3%	0.30	18 / 605
lymph node	0%	0	0 / 0	3%	0.16	1 / 29
muscle	0%	3.14	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0034260	Biological process	negative regulation of GTPase activity
GO_0050772	Biological process	positive regulation of axonogenesis
GO_0010976	Biological process	positive regulation of neuron projection development
GO_0050918	Biological process	positive chemotaxis
GO_0007162	Biological process	negative regulation of cell adhesion
GO_0010593	Biological process	negative regulation of lamellipodium assembly
GO_0001938	Biological process	positive regulation of endothelial cell proliferation
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0043087	Biological process	regulation of GTPase activity
GO_0030336	Biological process	negative regulation of cell migration
GO_0008360	Biological process	regulation of cell shape
GO_0071526	Biological process	semaphorin-plexin signaling pathway
GO_0007399	Biological process	nervous system development
GO_0060326	Biological process	cell chemotaxis
GO_0002116	Cellular component	semaphorin receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0009986	Cellular component	cell surface
GO_0017154	Molecular function	semaphorin receptor activity
GO_0019904	Molecular function	protein domain specific binding
GO_0098632	Molecular function	cell-cell adhesion mediator activity
GO_0051022	Molecular function	Rho GDP-dissociation inhibitor binding
GO_0005515	Molecular function	protein binding

Gene name	PLXNB3
Protein name	Plexin-B3 Plexin B3
Synonyms	KIAA1206 PLXN6
Description	FUNCTION: Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. .
Accessions	ENST00000411613.5 Q9ULL4 ENST00000538966.5 [Q9ULL4-2] ENST00000448847.1 H7C3L0 ENST00000361971.10 [Q9ULL4-1] H7C0P4 H7BZV5 ENST00000455214.1

PLXNB3 report