Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 19 studies | 40% ± 16% | |
non-classical monocyte | 15 studies | 31% ± 15% | |
classical monocyte | 14 studies | 27% ± 12% | |
type I pneumocyte | 10 studies | 31% ± 8% | |
epithelial cell | 10 studies | 33% ± 18% | |
monocyte | 9 studies | 21% ± 4% | |
basal cell | 8 studies | 34% ± 12% | |
macrophage | 8 studies | 24% ± 9% | |
plasmacytoid dendritic cell | 8 studies | 23% ± 7% | |
respiratory goblet cell | 7 studies | 31% ± 12% | |
club cell | 6 studies | 32% ± 9% | |
fibroblast | 6 studies | 19% ± 3% | |
goblet cell | 6 studies | 28% ± 9% | |
secretory cell | 5 studies | 30% ± 12% | |
squamous epithelial cell | 4 studies | 49% ± 15% | |
abnormal cell | 4 studies | 26% ± 5% | |
endothelial cell | 4 studies | 28% ± 11% | |
microglial cell | 4 studies | 22% ± 4% | |
astrocyte | 4 studies | 22% ± 3% | |
ionocyte | 3 studies | 25% ± 5% | |
myeloid cell | 3 studies | 26% ± 1% | |
pericyte | 3 studies | 17% ± 2% | |
dendritic cell | 3 studies | 38% ± 12% | |
enteroendocrine cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 20289.72 | 1445 / 1445 | 100% | 284.79 | 183 / 183 |
prostate | 100% | 27983.95 | 245 / 245 | 100% | 252.21 | 501 / 502 |
uterus | 100% | 23186.16 | 170 / 170 | 100% | 220.82 | 458 / 459 |
stomach | 100% | 24951.06 | 359 / 359 | 99% | 207.49 | 283 / 286 |
intestine | 100% | 17204.38 | 966 / 966 | 99% | 185.41 | 520 / 527 |
ovary | 100% | 26874.66 | 180 / 180 | 98% | 199.07 | 423 / 430 |
breast | 100% | 15529.12 | 459 / 459 | 98% | 178.53 | 1099 / 1118 |
lung | 100% | 23352.56 | 578 / 578 | 98% | 213.05 | 1132 / 1155 |
skin | 100% | 21238.40 | 1809 / 1809 | 98% | 177.37 | 462 / 472 |
thymus | 100% | 32672.30 | 653 / 653 | 98% | 325.32 | 592 / 605 |
pancreas | 98% | 11579.93 | 322 / 328 | 99% | 216.63 | 177 / 178 |
bladder | 100% | 18093.24 | 21 / 21 | 97% | 199.30 | 491 / 504 |
kidney | 100% | 25765.43 | 89 / 89 | 97% | 230.59 | 877 / 901 |
liver | 100% | 15142.36 | 226 / 226 | 95% | 150.30 | 387 / 406 |
adrenal gland | 100% | 25892.35 | 258 / 258 | 93% | 104.18 | 214 / 230 |
brain | 85% | 9801.14 | 2247 / 2642 | 97% | 93.20 | 681 / 705 |
eye | 0% | 0 | 0 / 0 | 100% | 143.53 | 80 / 80 |
spleen | 100% | 30793.34 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 242.01 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 233.96 | 1 / 1 |
blood vessel | 100% | 20849.84 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 12391.17 | 1202 / 1204 | 0% | 0 | 0 / 0 |
heart | 94% | 7568.12 | 806 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 91.82 | 27 / 29 |
peripheral blood | 72% | 6020.08 | 668 / 929 | 0% | 0 | 0 / 0 |
muscle | 18% | 904.47 | 141 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050772 | Biological process | positive regulation of axonogenesis |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_2001222 | Biological process | regulation of neuron migration |
GO_0007162 | Biological process | negative regulation of cell adhesion |
GO_0001932 | Biological process | regulation of protein phosphorylation |
GO_1904861 | Biological process | excitatory synapse assembly |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0043087 | Biological process | regulation of GTPase activity |
GO_0030334 | Biological process | regulation of cell migration |
GO_0001843 | Biological process | neural tube closure |
GO_0045727 | Biological process | positive regulation of translation |
GO_0007420 | Biological process | brain development |
GO_0008360 | Biological process | regulation of cell shape |
GO_0071526 | Biological process | semaphorin-plexin signaling pathway |
GO_0007405 | Biological process | neuroblast proliferation |
GO_0002116 | Cellular component | semaphorin receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0009986 | Cellular component | cell surface |
GO_0017154 | Molecular function | semaphorin receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PLXNB2 |
Protein name | Plexin-B2 (MM1) PLXNB2 protein Plexin B2 |
Synonyms | KIAA0315 |
Description | FUNCTION: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling (By similarity). Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development (By similarity). Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248' (By similarity). Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development (By similarity). Regulates the migration of cerebellar granule cells in the developing brain (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton . Plays a role in axon guidance, invasive growth and cell migration . May modulate the activity of RAC1 and CDC42 (By similarity). . |
Accessions | A6QRG9 A6QRH1 E2PU09 H0Y6J7 ENST00000359337.9 ENST00000432455.5 ENST00000449103.5 ENST00000425954.1 ENST00000427829.1 H0Y7X5 Q2TBE4 A0PK02 ENST00000411680.1 ENST00000434732.1 O15031 |