Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 31 studies | 38% ± 16% | |
pericyte | 14 studies | 27% ± 8% | |
oligodendrocyte precursor cell | 14 studies | 41% ± 20% | |
smooth muscle cell | 9 studies | 25% ± 6% | |
myofibroblast cell | 8 studies | 37% ± 12% | |
connective tissue cell | 7 studies | 31% ± 13% | |
type I pneumocyte | 7 studies | 27% ± 8% | |
mesothelial cell | 6 studies | 38% ± 19% | |
adipocyte | 5 studies | 28% ± 11% | |
endothelial cell | 4 studies | 24% ± 4% | |
astrocyte | 4 studies | 28% ± 13% | |
oligodendrocyte | 4 studies | 21% ± 7% | |
adventitial cell | 3 studies | 29% ± 5% | |
chondrocyte | 3 studies | 39% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 10554.96 | 578 / 578 | 91% | 5.86 | 1047 / 1155 |
kidney | 99% | 2991.80 | 88 / 89 | 89% | 19.75 | 806 / 901 |
esophagus | 95% | 2577.27 | 1372 / 1445 | 92% | 5.96 | 169 / 183 |
breast | 99% | 3814.30 | 455 / 459 | 77% | 3.34 | 857 / 1118 |
ovary | 100% | 8387.19 | 180 / 180 | 72% | 2.46 | 310 / 430 |
thymus | 98% | 2291.32 | 643 / 653 | 72% | 1.95 | 434 / 605 |
uterus | 99% | 9523.18 | 169 / 170 | 69% | 3.49 | 316 / 459 |
brain | 65% | 684.11 | 1711 / 2642 | 94% | 5.61 | 665 / 705 |
skin | 92% | 2369.77 | 1669 / 1809 | 67% | 3.23 | 315 / 472 |
prostate | 96% | 2018.13 | 236 / 245 | 61% | 1.41 | 307 / 502 |
intestine | 99% | 3457.71 | 957 / 966 | 49% | 1.60 | 259 / 527 |
bladder | 95% | 2364.10 | 20 / 21 | 52% | 1.84 | 260 / 504 |
stomach | 79% | 1523.20 | 284 / 359 | 65% | 2.65 | 187 / 286 |
pancreas | 41% | 405.30 | 134 / 328 | 91% | 4.82 | 162 / 178 |
adrenal gland | 85% | 1010.89 | 220 / 258 | 37% | 1.12 | 84 / 230 |
blood vessel | 100% | 3731.30 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 4615.85 | 1189 / 1204 | 0% | 0 | 0 / 0 |
spleen | 97% | 2004.13 | 234 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 60% | 1.80 | 27 / 45 |
heart | 48% | 704.53 | 410 / 861 | 0% | 0 | 0 / 0 |
liver | 12% | 101.76 | 26 / 226 | 23% | 1.81 | 92 / 406 |
eye | 0% | 0 | 0 / 0 | 29% | 0.92 | 23 / 80 |
muscle | 19% | 205.21 | 153 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 3.32 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030835 | Biological process | negative regulation of actin filament depolymerization |
GO_0016604 | Cellular component | nuclear body |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0030027 | Cellular component | lamellipodium |
GO_0030864 | Cellular component | cortical actin cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | PLEKHH2 |
Protein name | Pleckstrin homology, MyTH4 and FERM domain containing H2 Pleckstrin homology domain-containing family H member 2 |
Synonyms | KIAA2028 |
Description | FUNCTION: In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia. |
Accessions | ENST00000282406.9 [Q8IVE3-1] ENST00000490038.1 Q8IVE3 E5RGK1 ENST00000491692.5 H0YBV1 |