PLEK2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLEK2 at tissue level.

III. Associated gene sets

GO_0030036Biological processactin cytoskeleton organization
GO_0035556Biological processintracellular signal transduction
GO_0120034Biological processpositive regulation of plasma membrane bounded cell projection assembly
GO_0031258Cellular componentlamellipodium membrane
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0080025Molecular functionphosphatidylinositol-3,5-bisphosphate binding
GO_0032266Molecular functionphosphatidylinositol-3-phosphate binding
GO_0043325Molecular functionphosphatidylinositol-3,4-bisphosphate binding

IV. Literature review

[source]
Gene namePLEK2
Protein namePleckstrin 2
Pleckstrin-2
Synonyms
DescriptionFUNCTION: May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.

AccessionsENST00000216446.9
ENST00000553387.1
H0YIZ5
ENST00000556532.1
H0YJ64
G3V337
ENST00000555803.5
H0YJD0
Q9NYT0
ENST00000554395.1