PLA2G4F | OmnibusX

Name	Number of supported studies	Average coverage
type II pneumocyte	4 studies	25% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLA2G4F at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	79%	2379.57	193 / 245	99%	26.78	495 / 502
stomach	52%	684.85	185 / 359	72%	9.06	206 / 286
lung	58%	4418.93	338 / 578	64%	7.61	743 / 1155
intestine	38%	1235.06	369 / 966	77%	9.88	405 / 527
kidney	100%	2828.30	89 / 89	12%	9.53	108 / 901
esophagus	38%	924.01	553 / 1445	71%	11.06	130 / 183
bladder	33%	601.38	7 / 21	76%	10.32	382 / 504
ureter	0%	0	0 / 0	100%	3.78	1 / 1
thymus	57%	855.30	374 / 653	36%	5.21	216 / 605
skin	72%	15273.60	1302 / 1809	8%	1.48	36 / 472
tonsil	0%	0	0 / 0	67%	7.79	30 / 45
muscle	64%	867.27	511 / 803	0%	0	0 / 0
breast	6%	55.69	28 / 459	46%	3.23	518 / 1118
uterus	1%	69.94	2 / 170	46%	5.52	211 / 459
pancreas	0%	2.87	1 / 328	31%	1.94	56 / 178
ovary	1%	4.68	1 / 180	4%	0.25	18 / 430
liver	0%	0	0 / 226	3%	0.25	14 / 406
heart	3%	19.21	22 / 861	0%	0	0 / 0
adipose	1%	15.51	7 / 1204	0%	0	0 / 0
brain	0%	2.29	7 / 2642	0%	0.00	1 / 705
blood vessel	0%	4.57	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	0%	0	0 / 230
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0071236	Biological process	cellular response to antibiotic
GO_0036148	Biological process	phosphatidylglycerol acyl-chain remodeling
GO_0071407	Biological process	cellular response to organic cyclic compound
GO_0001516	Biological process	prostaglandin biosynthetic process
GO_0046475	Biological process	glycerophospholipid catabolic process
GO_0050482	Biological process	arachidonic acid secretion
GO_0032587	Cellular component	ruffle membrane
GO_0005829	Cellular component	cytosol
GO_0031982	Cellular component	vesicle
GO_0005739	Cellular component	mitochondrion
GO_0004622	Molecular function	lysophospholipase activity
GO_0005509	Molecular function	calcium ion binding
GO_0008970	Molecular function	phospholipase A1 activity
GO_0047498	Molecular function	calcium-dependent phospholipase A2 activity
GO_0005544	Molecular function	calcium-dependent phospholipid binding

Gene name	PLA2G4F
Protein name	Phospholipase A2 (EC 3.1.1.4) PLA2G4F protein Cytosolic phospholipase A2 zeta (cPLA2-zeta) (EC 3.1.1.4) (Phospholipase A2 group IVF) Phospholipase A2 group IVF
Synonyms
Description	FUNCTION: Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators . Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) . Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis . In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs) . .
Accessions	H3BSG9 Q68DD2 A6H8K5 ENST00000397272.7 [Q68DD2-1] H3BNW4 ENST00000565553.1 A5PKZ7 H3BMD0 H7BXJ8 A2RRC4 Q8IUP3 ENST00000290497.11 ENST00000562320.1 H3BPX7 ENST00000569985.5 ENST00000561627.5

PLA2G4F report