PLA2G4B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLA2G4B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	100%	4193.09	170 / 170	10%	0.17	48 / 459
lung	99%	3282.99	575 / 578	6%	0.10	69 / 1155
bladder	100%	3378.00	21 / 21	5%	0.08	27 / 504
esophagus	99%	3978.07	1431 / 1445	4%	0.07	8 / 183
thymus	100%	6859.14	653 / 653	2%	0.03	11 / 605
prostate	100%	6812.82	244 / 245	2%	0.02	9 / 502
breast	100%	3112.39	458 / 459	1%	0.01	11 / 1118
ovary	100%	5705.88	180 / 180	0%	0.01	2 / 430
spleen	100%	3903.99	241 / 241	0%	0	0 / 0
intestine	100%	2595.01	963 / 966	0%	0.00	1 / 527
kidney	99%	2858.37	88 / 89	1%	0.01	7 / 901
pancreas	99%	2216.67	326 / 328	0%	0	0 / 178
stomach	98%	2085.44	353 / 359	0%	0	0 / 286
adipose	97%	2218.33	1169 / 1204	0%	0	0 / 0
brain	92%	4644.63	2418 / 2642	3%	0.05	23 / 705
liver	94%	1780.55	212 / 226	0%	0	0 / 406
blood vessel	94%	1793.21	1252 / 1335	0%	0	0 / 0
adrenal gland	88%	1532.45	227 / 258	0%	0	0 / 230
peripheral blood	79%	1446.10	731 / 929	0%	0	0 / 0
heart	76%	1240.52	655 / 861	0%	0	0 / 0
skin	73%	7009.24	1318 / 1809	0%	0.00	1 / 472
muscle	39%	506.79	314 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.07	2 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0036148	Biological process	phosphatidylglycerol acyl-chain remodeling
GO_0006954	Biological process	inflammatory response
GO_0019722	Biological process	calcium-mediated signaling
GO_0019369	Biological process	arachidonic acid metabolic process
GO_0046475	Biological process	glycerophospholipid catabolic process
GO_0007567	Biological process	parturition
GO_0031901	Cellular component	early endosome membrane
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0004623	Molecular function	phospholipase A2 activity
GO_0004622	Molecular function	lysophospholipase activity
GO_0102545	Molecular function	phosphatidyl phospholipase B activity
GO_0005509	Molecular function	calcium ion binding
GO_0008970	Molecular function	phospholipase A1 activity
GO_0047498	Molecular function	calcium-dependent phospholipase A2 activity
GO_0005544	Molecular function	calcium-dependent phospholipid binding

Gene name	PLA2G4B
Protein name	Phospholipase A2 group IVB Cytosolic phospholipase A2 beta (cPLA2-beta) (EC 3.1.1.4) (Lysophospholipase A1 group IVB) (EC 3.1.1.5) (Phospholipase A2 group IVB)
Synonyms
Description	FUNCTION: Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling. .; FUNCTION: [Isoform 3]: Calcium-dependent phospholipase A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-2 position of phosphatidylethanolamines, producing lysophospholipids that may be used in deacylation-reacylation cycles. Hydrolyzes lysophosphatidylcholines with low efficiency but is inefficient toward phosphatidylcholines. .; FUNCTION: [Isoform 5]: Calcium-dependent phospholipase A1 and A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-1 or sn-2 position of diacyl phospholipids (phospholipase A1 and A2 activity, respectively), producing lysophospholipids that may be used in deacylation-reacylation cycles. Can further hydrolyze lysophospholipids enabling complete deacylation. Has no activity toward alkylacyl phospholipids. .
Accessions	H3BSX5 P0C869 ENST00000569354.1 ENST00000458483.4 [P0C869-1] ENST00000452633.5 [P0C869-1]

PLA2G4B report