PKD1L1 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	41% ± 15%	Explore
interneuron	3 studies	45% ± 18%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PKD1L1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	95%	84.24	20 / 21	25%	0.98	128 / 504
intestine	98%	78.91	947 / 966	14%	0.24	76 / 527
breast	99%	186.63	454 / 459	13%	0.24	149 / 1118
lung	99%	142.38	572 / 578	5%	0.09	60 / 1155
thymus	98%	157.69	637 / 653	4%	0.07	25 / 605
spleen	100%	65.20	241 / 241	0%	0	0 / 0
heart	100%	277.36	859 / 861	0%	0	0 / 0
adipose	100%	196.70	1199 / 1204	0%	0	0 / 0
muscle	99%	121.61	795 / 803	0%	0	0 / 0
uterus	96%	67.98	164 / 170	2%	0.05	10 / 459
brain	93%	78.49	2458 / 2642	5%	0.09	34 / 705
esophagus	84%	105.06	1209 / 1445	9%	0.16	17 / 183
skin	69%	35.46	1246 / 1809	20%	0.64	94 / 472
stomach	69%	37.22	247 / 359	19%	0.33	55 / 286
ovary	77%	32.70	139 / 180	10%	0.22	41 / 430
prostate	84%	45.89	205 / 245	2%	0.03	8 / 502
kidney	73%	44.12	65 / 89	8%	0.15	75 / 901
blood vessel	81%	55.56	1084 / 1335	0%	0	0 / 0
adrenal gland	32%	11.83	82 / 258	19%	0.29	44 / 230
liver	37%	14.15	84 / 226	1%	0.05	5 / 406
pancreas	31%	10.88	101 / 328	3%	0.40	6 / 178
peripheral blood	16%	5.07	146 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	0.13	3 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0050982	Biological process	detection of mechanical stimulus
GO_0070986	Biological process	left/right axis specification
GO_0098609	Biological process	cell-cell adhesion
GO_0003127	Biological process	detection of nodal flow
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0060170	Cellular component	ciliary membrane
GO_0097730	Cellular component	non-motile cilium
GO_0005929	Cellular component	cilium
GO_0034704	Cellular component	calcium channel complex
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity

Gene name	PKD1L1
Protein name	Polycystin-1-like protein 1 (Polycystin-1L1) (PC1-like 1 protein) (Polycystic kidney disease protein 1-like 1) Polycystin 1 like 1, transient receptor potential channel interacting
Synonyms	UNQ5785/PRO19563
Description	FUNCTION: Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning. .
Accessions	Q8TDX9 ENST00000289672.7 [Q8TDX9-1] A0A8I5QKU1 A0A3B3IRH7 ENST00000690269.1 ENST00000648482.1 ENST00000686775.1 ENST00000685709.1 A0A8I5KS31 H7C083 ENST00000433506.2 A0A8I5KWV8

PKD1L1 report